Amphioxus PE glucoprotein and its production process

Abstract

The present invention relates to new lung cancer treating medicine. By means of biotechnology, slug PE4 glycoprotein as one kind of natural lung cancer treating medicine is extracted from slug as one crop harming mollusk. The extracted slug PE4 glycoprotein is further prepared into capsule, granule, tablet, injection or powder for injection. These slug PE4 glycoprotein preparations can kill lung cancer cell directly and effectively and reduce the main symptoms of lung cancer patient and has no acute toxic effect like that of chemotherapy and radiotherapy.

Description

[technical field] [0001] The invention relates to a new anti-lung cancer drug, in particular to a natural anti-lung cancer drug—slug PE extracted from mollusc slugs by applying biotechnology 4 Glycoprotein, and capsules, granules, tablets, pills, dripping pills, powders, syrups, aqueous injections, and freeze-dried powder injections made from them. [Background technique] [0002] 1. Lung cancer, a malignant tumor, has become the number one killer threatening human health [0003] The incidence of lung cancer has been increasing at a rate of 11.90% in the past 10 years with the aggravation of environmental pollution. In 2000, there were more than 10 million new cases of malignant tumors in the world, and 6.2 million deaths, including 1.239 million new cases of lung cancer, accounting for 12.32% of the total cancer cases, and 1.103 million deaths from lung cancer, accounting for 17.77% of the total deaths. top. At present, 1.5-1.8 million people die of lung cancer every yea...

AI Technical Summary

Problems solved by technology

[0004] 2. There are many methods and related drugs for the treatment of lung cancer, but they all have certain limitations

But once clinically diagnosed as lung cancer, 80% of patients have just lost the chance of surgical resection; and radiation therapy has local limitations and damage to normal tissues; chemical (drug) therapy has universal cytotoxicity and its Dose limitation; especially severe toxic and side effects on liver, kidney, bone marrow and digestive system, greatly restricting the therapeutic effect of lung cancer

Emerging interventional therapy has a certain effect on the primary tumor, but it is difficult to deal with the constantly sporadic metastases; modern molecular targeted (gene) therapy has brought hope to lung cancer patients, but its vector construction, cross-linking of vector and warhead and Many issues such as its distribution in the body and changes in the metabolic process are still under discussion.

[0006] 3. Traditional Chinese medicine has a long history, but its curative effect on lung cancer is uncertain, and there is no breakthrough progress

Although the existing traditional Chinese medicines for the treatment of lung cancer emerge in endlessly, and the dosage forms include single ingredients, monomers and compound prescriptions, but whether the modern Chinese medicines such as "Kanglaite Injection" that have been involved in clinical research in the United States and Russia, have a definite curative effect on lung cancer? not yet recognized