570results about How to "Quick sorting" patented technology

The present invention provides methods for determining a nucleic acid sequence by performing successive cycles of duplex extension along a single stranded template. The cycles comprise steps of extension, ligation, and, preferably, cleavage. In certain embodiments the methods make use of extension probes containing phosphorothiolate linkages and employ agents appropriate to cleave such linkages. In certain embodiments the methods make use of extension probes containing an abasic residue or a damaged base and employ agents appropriate to cleave linkages between a nucleoside and an abasic residue and/or agents appropriate to remove a damaged base from a nucleic acid. The invention provides methods of determining information about a sequence using at least two distinguishably labeled probe families. In certain embodiments the methods acquire less than 2 bits of information from each of a plurality of nucleotides in the template in each cycle. In certain embodiments the sequencing reactions are performed on templates attached to beads, which are immobilized in or on a semi-solid support. The invention further provides sets of labeled extension probes containing phosphorothiolate linkages or trigger residues that are suitable for use in the method. In addition, the invention includes performing multiple sequencing reactions on a single template by removing initializing oligonucleotides and extended strands and performing subsequent reactions using different initializing oligonucleotides. The invention further provides efficient methods for preparing templates, particularly for performing sequencing multiple different templates in parallel. The invention also provides methods for performing ligation and cleavage. The invention also provides new libraries of nucleic acid fragments containing paired tags, and methods of preparing microparticles having multiple different templates (e.g., containing paired tags) attached thereto and of sequencing the templates individually. The invention also provides automated sequencing systems, flow cells, image processing methods, and computer-readable media that store computer-executable instructions (e.g., to perform the image-processing methods) and/or sequence information. In certain embodiments the sequence information is stored in a database.

The present invention provides assay systems and related methods for determining genetic abnormalities in mixed samples comprising cell free DNA from both normal and putative genetically atypical cells. Exemplary mixed samples for analysis using the assay systems of the invention include samples comprising both maternal and fetal cell free DNA and samples that contain DNA from normal cells and circulating cancerous cells.

The present disclosure provides methods for determining a nucleic acid sequence by performing successive cycles of duplex extension along a single stranded template. The cycles typically comprise steps of extension, ligation, and cleavage. In certain embodiments, the methods make use of extension probes containing phosphorothiolate linkages and agents capable of cleaving such linkages. Methods of determining information about a sequence using at least two distinguishably labeled probe families are provided, as are methods of performing multiple sequencing reactions on a single template. Automated sequencing systems, flow cells, image processing methods, and computer-readable media that store computer-executable instructions and/or sequence information that can be used in accordance with such methods are also provided. In certain embodiments, blocking oligonucleotides are provided to facilitate sequencing using disclosed methods.

The present invention provides assay systems and related methods for determining genetic abnormalities in mixed samples comprising cell free DNA from both normal and putative genetically atypical cells. Exemplary mixed samples for analysis using the assay systems of the invention include samples comprising both maternal and fetal cell free DNA and samples that contain DNA from normal cells and circulating cancerous cells.

A system and method for online, essentially instantaneous analyses of ore compositions on a moving belt use laser-induced break-down spectroscopy (LIBS), wherein intensity ratios of emission lines characteristic of specific minerals or ions are calculated on areas of the moving belt, with elevated contents of identifying ions or species being detectable. The ratios are derived from ions present in the sample that differentiate a first substance from a second substance, thus allowing sorting of the samples. The substance may include an ion, an element, or a compound.

The present invention relates to the field of property or real estate. In one form, the invention relates to the rating of property. In another form, the present invention relates to the ranking of property based on various inputs into the system and method of the present invention. The rating and/or ranking is determined in accordance with a numerical value.

The invention is directed to methods for determining clonotypes and clonotype profiles in assays for analyzing immune repertoires by high throughput nucleic acid sequencing of somatically recombined immune molecules. In one aspect, the invention comprises generating a clonotype profile from an individual by generating sequence reads from a sample of recombined immune molecules; forming from the sequence reads a sequence tree representing candidate clonotypes each having a frequency; coalescing with a highest frequency candidate clonotype any lesser frequency candidate clonotypes whenever such lesser frequency is below a predetermined value and whenever a sequence difference therebetween is below a predetermined value to form a clonotype. After such coalescence, the candidate clonotypes is removed from the sequence tree and the process is repeated. This approach permits rapid and efficient differentiation of candidate clonotypes with genuine sequence differences from those with experimental or measurement errors, such as sequencing errors.

The invention discloses a method for arranging steering buses in sequence in a bus stop at the inner side of a road. The method comprises the steps that according to collected bus real-time information, time when one bus reaches a downstream intersection is predicted, passenger delay caused by steering and a signal phase sequence of the bus is analyzed, so that an optimal scheme of the bus sequence is generated, a driving waiting zone and a signal control light are arranged at the bus stop at the inner side of the road, and therefore the bus operation sequence is effectively adjusted. According to the method for arranging the steering buses in sequence in the bus stop at the inner side of the road, from the perspective of bus operation time and with the combination of bus operation experience data and real-time collected data, the time when one bus reaches the downstream intersection is accurately predicted, passenger delay caused by the driving sequence of the steering buses is accurately judged according to an original green light interval time table, and the reliable steering bus sequence is formed; the driving waiting zone is arranged at the bus stop, so that under the condition of linkage control of an outlet portion and the signal light of the driving waiting zone, the buses are rapidly and effectively lined, total delay of the steering buses in the intersection is reduced, prior passage of the buses at the signal intersection of the downstream is guaranteed, and the operation efficiency of the buses is effectively improved.

The invention discloses a logistic commodity sorting device and system. The logistic commodity sorting device comprises an upper computer processing center, a conveying belt device, an automatic scanner device, a signal detection device, a sorting power component device and separating channels. When logistic commodities are placed on the conveying belt device, the automatic scanner device reads information of the logistic commodities and transmits the information to the upper computer processing center, the signal detection device transmits the information to the upper computer processing center when detecting the information of the logistic commodities, the upper computer processing center sends action commands according to the obtained information, the sorting power component device executes the action commands and pushes the corresponding commodities into the corresponding separating channels, and therefore the logistic sorting process can be realized. According to the technical scheme, the logistic commodities can be effectively, quickly and accurately sorted. The logistic commodity sorting device and system are suitable for the sorting work of medium-small logistic sorting stations and can improve the logistic sorting efficiency, lower the labor intensity and lower the labor cost.

The invention relates to an evaluation method of the power supply reliability of a distribution network based on demand response. The method includes steps: 1) building a demand response model based on time-of-use power price; 2) building an improved load optimization model based on demand response; 3) performing optimization and classification of an optimized load curve by employing a bisection method, and solving the optimal classification number; and 4) establishing an improved cluster load analysis reliability evaluation algorithm based on the bisection method; and changing a cluster load interval into a monotonic increasing trend for convenient calculation. According to the method, the problem of the evaluation of the power supply reliability of the distribution network based on demand response is effectively solved.

The invention discloses a micro luminous display device and a manufacturing method thereof. The manufacturing method comprises the following steps: providing a tank containing a liquid; disposing at least a carrying plate with several recessed regions in the tank, and the carrying plate being immersed in the liquid; dropping several lighting devices into the liquid, wherein each of the lighting devices includes at least two conductive pads, and one of the two conductive pads includes a magnetic material; applying a magnetic field for the lighting devices and the lighting devices will dispose within the recessed regions of the carrying plate; removing the carrying plate with the lighting devices out of the tank, and electrically assembling the lighting devices to an array substrate.

The invention discloses a hair ring split charging machine. At present, ring packaging is manually operated, and the packaging efficiency is low. The hair ring split charging machine comprises a feeding hopper, a rotation mechanism, a transverse moving screening mechanism, a material dividing device, counters and a discharging device; the rotation mechanism is arranged at the bottom of a discharging hopper, the transverse moving screening mechanism is arranged below the rotation mechanism, and raw materials are evenly discharged; three split strips are arranged between a conveying belt mechanism of the material dividing device and a screen of the transverse moving screening mechanism, the position, between every two adjacent split strips, of the output end of the conveying belt mechanism is provided with one counter, and the discharging device is arranged below the counters and comprises a discharging barrel, first rotating shafts, second rotating shafts and a flow combining part; and the discharging barrel is divided into two discharging chambers, first discharging clamping rings are fixed to the first rotating shafts in the discharging chambers, clamping grooves in the tops of the first discharging clamping rings are fixed to first baffles, second discharging clamping rings are fixed to the second rotating shafts, and two second baffles are fixed in two clamping grooves in the bottoms of the second discharging clamping rings. A gap of flexible material split charging in industrial production is filled up by means of the hair ring split charging machinej.

The invention discloses a method of rearranging desktop icons. The method comprises the steps: judging whether a switchover gesture is received or not; recording an initial desktop state according to a judging result, and confirming a touch position of the switchover gesture; generating a touch control button according to the touch position; and controlling the touch control button to enable a plurality of desktop icons to be rearranged according to the indicated direction of the touch control button. Compared with the prior art, the method of rearranging the desktop icons has the advantages that when a mobile terminal is held by a single hand, the touch control button is generated according to the touch position of the switchover gesture, so that the desktop icons which are arranged in a humanized mode and obtained through the method can enable the desktop icons on which a user wants to operate to be within a range which can be touched by a finger, accordingly operation on all desktop icons is achieved, and at the same time, convenience is brought to the user. The invention further discloses the touch type mobile terminal with a function of rearranging the desktop icons.

The invention relates to the bearing trench automatic selecting system. It aims to the big scatter of inside and outside liners of the bearing in machining, randomly selecting with low matching rate issue, starting with categorization of dimensions of the trenches, selecting rolling ball and the inner liner based on the dimension of the trench size. Currently, manual selection is used with big precision and efficiency change rate. It comprises the selection glide path on the fixed frame, drive mechanism fixed on the frame, support and drive mechanism fixed on the said frame, storage cabin installed inside the frame. It is selected based on the automatic measurement of the inside and outside trench dimensions.

The invention discloses an arranging device for installing pipetting tips into a tip box. The arranging device is composed of a driving device, a tip arranging device and an object placing platform. The driving device conveys the pipetting tips to clamping slots of the tip arranging device. A plurality of pipetting tips are vertically erected in the clamping slots, wherein openings of the pipetting tips are arranged upwards. Push plate assemblies which are located at the two ends of the clamping slots tightly rank all the pipetting tips which are located in the clamping slots. The tip arranging device feeds a row of pipetting tips in the clamping slots into a row of hole positions of the tip box, the clamping slots of the push plate assemblies are separated, the pipetting tips drop into the tip box after separating from the clamping slots, the tip arranging device is restored to an original state, the driving device continues to convey the pipetting tips which are scatteredly distributed to the tip arranging device and conducts arrangement of the pipetting tips of a next row of hole positions, and the process is repeated until the pipetting tips are ranked in the whole tip box in order. Staff in a laboratory only needs to place the scattered pipetting tips into the device, and then the device can automatically achieve arranging and inserting of the pipetting tips, so that the arranging device for installing the pipetting tips into the tip box is very convenient to use.

The invention discloses an automatic arrangement device for storage battery packaging lines. The automatic arrangement device for the storage battery packaging lines comprises a rack, a horizontal conveying device, a stopping mechanism, a turning mechanism, a transverse pushing mechanism and a neatening platform, wherein the stopping mechanism comprises at least two stopping plates and a stopping plate driving device; the stopping plate driving device can drive the stopping plates to slidably stop conveyance of storage batteries or to release the storage batteries; the turning mechanism comprises a turning plate and a turning plate driving device; the turning plate is provided with a turning inclined plane; an obtuse angle is formed between the conveying direction and the turning inclined plane; the neatening platform is provided with a right-angle positioning plate and a neatening pushing device; by using the transverse pushing mechanism, arranged storage batteries are transversely pushed to the neatening platform and are abutted to the right-angle positioning plate; and the neatening pushing device pushes the storage batteries to a right-angle position of the right-angle positioning plate. By using the automatic arrangement device, the storage batteries which are conveyed in the longitudinal direction can be steered at an angle of 90 degrees and then are arranged accurately, the problems that the arrangement mode of the present structure is inaccurate and the efficiency is low are solved, and the storage battery arrangement efficiency and the storage battery arrangement effect are improved.

The invention discloses a rib marking method, device and equipment and a training method of an image segmentation model, and the method comprises the steps: obtaining a to-be-identified image; Whereinthe image to be identified comprises a CT image; Inputting the to-be-identified image into an image segmentation model to obtain a segmentation result; Wherein the segmentation result comprises a ribsegmentation result and a rib center line segmentation result; And performing rib sorting and marking based on the segmentation result. According to the invention, rib adhesion and fracture conditions can be well handled, and each rib can be quickly sorted and marked.

The invention discloses a sorting robot of a laser cutting machine and a part sorting method of the sorting robot and belongs to the field of machine tools. A Y-axis support seat comprise a Y-axis longitudinal support seat and a Y-axis transverse support seat; the Y-axis longitudinal support seat is matched with a rail on an X-axis support seat through a sliding mechanism; a Z-axis support seat and the Y-axis transverse support seat are connected through a connecting piece; a C-axis support seat is matched with the Z-axis support seat; the C-axis support seat is driven by a driving device and is connected with a sorting tool; the sorting tool comprises a master panel; a plurality of air cylinders are arranged on the master panel in an array; and each air cylinder is separately connected with a sucking disc. The sorting robot of the laser cutting machine can replace the laser cutting machine for manual sorting, can identify a finished product cut by laser, and rapidly sort and stack the cut finished product.

A mail processing system including a franking machine for franking mail items, which franking machine is connected to a first server that is itself connected to a second server in communication with a sorting machine, the franking machine including scanner means for scanning the destination addresses borne on the mail items as said mail items are inserted, storage means for storing the digital images of the addresses scanned in this way, in association with respective unique identification numbers, and communications means for periodically transferring the digital images as indexed in this way to the first server, the first or second server further including means for extracting determined data from the digital images, which data, associated with said unique identification numbers, is suitable for enabling said sorting machine to be controlled automatically on receiving said franked mail items.