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Chinese medicine jewing tablet for treating hepatitis and its preparing method

A technology of chewable tablets and traditional Chinese medicine, which is applied in the field of medicine, can solve the problems of affecting bioavailability, easy mildew, and poor medical compliance of patients with dysphagia, and achieve the effect of improving bioavailability and guaranteeing curative effect

Inactive Publication Date: 2006-11-08
SHANGHAI YOUSEEN NEW MEDICINE EXPLOITION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, tablets have certain disadvantages, mainly as follows: due to the addition of more excipients during compression molding, the dissolution rate is poor, and even affects bioavailability; strong hygroscopicity, easy to mildew; and children and patients with dysphagia poor medical compliance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Active ingredient 300g of medicine, add lactose 500g, sorbitol 35g, mannitol 145g, citric acid 10g, aspartame 5g, mix uniformly, put in the granulator, add 30g of 10% starch slurry to make granule; The granules are mixed with 5g of magnesium stearate and compressed into tablets.

Embodiment 2

[0017] The active ingredient 200g of medicine, add lactose 640g, sorbitol 72g, mannitol 48g, citric acid 30g, aspartame 10g, mix uniformly, in the granulator, add the 10% starch slurry of 50g to make granule; The granules are mixed with 2g of magnesium stearate and compressed into tablets.

Embodiment 3

[0019] Active ingredient 500g of medicine, add lactose 300g, sorbitol 45g, mannitol 130g, citric acid 18g, aspartame 7g, mix uniformly, in the granulator, add 10% starch slurry of 20g to make granule; The granules are mixed with 4g of magnesium stearate and compressed into tablets.

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PUM

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Abstract

The present invention relates to medicine technology, and is new preparation form of hepatitis treating Chinese medicine, a chewing tablet. The new preparation form prepared through an advanced technological process has raised bioavailability and high curative effect, may be taken without need water and is especially suitable for children and patient with dysphagia.

Description

technical field [0001] The invention relates to the technical field of medicine, and relates to a traditional Chinese medicine composition for treating hepatitis diseases, a chewable tablet dosage form prepared with other auxiliary materials and a preparation method thereof. Background technique [0002] Hepatitis is a general term for inflammatory diseases of the liver. It is more common in acute, chronic, and infectious diseases caused by hepatitis viruses. It seriously endangers health and is one of the modern intractable diseases. According to statistics, the current hepatitis virus infection rate in my country is as follows: there are more than 30 million hepatitis patients nationwide, accounting for 2.31% of the total population; the hepatitis B virus surface antigen carrier rate is as high as 9.8%, and the population is about 120 million; nearly 30 million hepatitis C virus carriers %. About 280,000 people die from liver disease every year, accounting for 3.65% of the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K9/48A61P1/16A61P31/14A61P31/20
Inventor 玄振玉王勇
Owner SHANGHAI YOUSEEN NEW MEDICINE EXPLOITION