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Chinese medicine compound preparation for treating chronic hepatic disease and its preparing method

A technology for compound preparations and chronic liver diseases, which can be used in pharmaceutical formulations, antiviral agents, medical preparations containing active ingredients, etc., and can solve problems such as single dosage form, irritation, and easy moisture absorption

Active Publication Date: 2007-01-24
SHANGHAI HUANGHAI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Prior art (Chinese patent: 99113887.2), adopts the capsule preparation of Chinese medicine salvia miltiorrhiza, peach kernel, cordyceps hyphae etc. to have good anti-hepatic fibrosis effect to chronic hepatitis B liver fibrosis, but described capsule still has defects and Insufficient, such as: a single dosage form, easy to absorb moisture, and the capsule material is irritating to the gastrointestinal tract, etc., which affects the stability and exertion of the drug effect

Method used

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  • Chinese medicine compound preparation for treating chronic hepatic disease and its preparing method
  • Chinese medicine compound preparation for treating chronic hepatic disease and its preparing method
  • Chinese medicine compound preparation for treating chronic hepatic disease and its preparing method

Examples

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Effect test

Embodiment 1

[0059] The dried extracted extracts were crushed separately, mixed evenly according to the formula ratio, added with auxiliary materials, mixed evenly, granulated, dried, tabletted and coated according to the conventional method. The main ingredients and auxiliary materials are according to the following ratios: mixed extract powder 60.0%-80.0%, compressible starch 15.0%-20.0%, microcrystalline cellulose 3.0%-10.0%, sodium carboxymethyl starch 2.0%-10.0% %, magnesium stearate 0.1% to 0.4%.

Embodiment 2

[0061] The dried extracted extracts were crushed separately, mixed evenly according to the formula ratio, added with auxiliary materials, mixed evenly, and prepared capsules according to the conventional method. The main drug and auxiliary materials are prepared according to the following proportions: 65%-85% of mixed extract powder, 0%-35% of microcrystalline cellulose, and 0%-5% of calcium carbonate, which are uniformly mixed and packed into capsules.

Embodiment 3

[0063] The dried extracted extracts were crushed separately, mixed according to the proportion, and then added with auxiliary material dextrin to granulate. The main drug and auxiliary materials are prepared according to the following ratio: 60%-90% of mixed extract powder, 40%-10% of dextrin, mixed evenly, granulated according to the conventional method, dried at 60-65°C, and granulated to obtain the product.

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PUM

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Abstract

The present invention relates to belongs to the field of Chinese medicine technology, relates to compound Chinese medicine preparation for treating chronic hepatosis, and is especially compound Chinese medicine preparation for treating hepatitis and hepatic fibrosis and its preparation process. The compound Chinese medicine preparation is prepared with red sage, fermented aweto powder, peach kernel, pine pollen, gynostemma pentaphylla, schisandra extract and medicinal supplementary material, and may be in different orally taken preparation forms. The compound Chinese medicine preparation has high effect of preventing and treating hepatic fibrosis and treating hepatitis and no obvious toxic side effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy. It relates to a traditional Chinese medicine compound preparation for treating chronic liver diseases and a preparation method thereof. In particular, it relates to a traditional Chinese medicine compound preparation for treating hepatitis and liver fibrosis and a preparation method thereof. Background technique [0002] Liver fibrosis is the only way for various chronic liver diseases such as: chronic hepatitis B, alcoholic liver disease, fatty liver, etc. to develop into liver cirrhosis. It is one of the two most difficult problems in clinical treatment (etiological treatment and anti-hepatic fibrosis). According to relevant statistics, there are 150 million people with chronic hepatitis B virus infection in my country, of whom about 30 million are chronic hepatitis B patients. Everyone knows the dangers of chronic hepatitis. One is to infect others, and the other is to c...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P1/16A61P31/14A61P31/20
Inventor 张宁王成荣刘平卞化石张建华袁秀荣刘成海金要王平海波
Owner SHANGHAI HUANGHAI PHARMA
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