Hydrocortisone clyster agent and method for preparing the same

Abstract

The invention discloses a loosening enema and preparing method of kao hydrate, which comprises the following parts in each 6000ml: 9.0-11.0g kao hydrate, 11.6-14.2g Tween-80, 81.0-99.0g CMC-Na, 2.1-2.7g aethylum hydroxybenzoicum and pure water. the preparing method comprises the following steps: allocating 7.2-8.8% Tween-80; stirring; dissolving; adding kao hydrate to stir evenly; allocating 4.5-5.5% aethylum hydroxybenzoicum; boiling; adding CMC-Na; bulking; adding purified water to stir evenly.

Description

technical field [0001] The invention relates to an enema and a preparation method thereof, in particular to a hydrocortisone enema for treating ulcerative rectum and sigmoid colitis and a preparation method thereof. Background technique [0002] Ulcerative colitis (ulcerative colitis) has been listed by the World Health Organization as one of the modern refractory diseases. ) of continuous inflammation, its clinical features are recurrent diarrhea (mucus pus and blood in the stool) and abdominal pain, and may be accompanied by systemic symptoms such as fever or joint pain. This disease is difficult for a radical cure, often protracted and difficult to heal, and the course of disease is long, brings great misery to the patient. In recent years, the incidence rate in our country has increased significantly, and the incidence is showing a younger trend, and there is a certain rate of cancer in the chronic phase. [0003] At present, sulfasalazine (SASP) is often used for such...

AI Technical Summary

Problems solved by technology

However, there is only imported mesalazine enema on the market at present, its main component is 5-aminosalicylic acid, the price is very expensive, and each 60ml enema needs to cost 200 yuan, and it will be used 1-2 times a day. After 6-8 weeks, gradually reduce the dosage to maintain the application; therefore, the vast majority of patients in China cannot afford the cost