Wrinkle-improving external preparation for skin
A skin external preparation and wrinkle technology, applied in the field of skin external preparations for improving wrinkles, can solve the problems of poor usability, poor use feeling, reduced wrinkle improvement effect, greasy feeling of skin film, etc., and achieves light feeling, excellent wrinkle improvement effect, The effect of increased film thickness
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preparation example 2-1
[0167] Add 150g IPD, 120g PTMG (molecular weight 1000), 5g CHDM and 10gDMBA to a four-necked flask equipped with a stirring device, a thermometer, a nitrogen conduit and a reflux condenser, then add 50g ethyl acetate as a solvent, and heat to 80°C using an oil bath , and allowed to react for 6 hours to obtain a prepolymer in which isocyanate groups remained. The prepolymer with residual isocyanate groups was cooled to 50°C, then dispersed into 800g of water containing 6g of potassium hydroxide under high-speed stirring, and then carried out at 50°C for 3 hours for chain extension reaction to make it reach a high molecular weight. The aforementioned ethyl acetate was recovered from the obtained aqueous liquid to obtain a substantially solvent-free polyurethane aqueous dispersion (20% by mass of polyurethane solids).
[0168] (average particle size: 170nm, film strength: 410kg / cm 2 , film elongation: 320%, film shrinkage: 11%)
preparation example 2-2
[0170] Add 150g IPD, 60g PTMG (molecular weight 1000), 40g PHMC (molecular weight 2000) and 10g DMBA in the four-neck flask equipped with stirring device, thermometer, nitrogen conduit and reflux condenser, then add 50g ethyl acetate as solvent, use oil The bath was heated to 80°C and allowed to react for 3 hours. Then, 2 g of N-methyldiethanolamine (NMDEtA) and 40 g of ethyl acetate were added, followed by a reaction at 80° C. for 3 hours to obtain a prepolymer in which isocyanate groups remained. The prepolymer with residual isocyanate groups was cooled to 50°C, then dispersed in 700g of water containing 6g of potassium hydroxide under high-speed stirring, and then carried out at 50°C for 3 hours for chain extension reaction to make it reach a high molecular weight. The aforementioned ethyl acetate was recovered from the obtained aqueous liquid to obtain a substantially solvent-free polyurethane aqueous dispersion (20% by mass of polyurethane solids).
[0171](average parti...
preparation example 1-1
[0181] Synthesis of Polyurethane Aqueous Dispersion
[0182] Add 150g IPD, 120g PTMG (molecular weight 1000), 5g CHDM and 10gDMBA to a four-necked flask equipped with a stirring device, a thermometer, a nitrogen conduit and a reflux condenser, then add 50g ethyl acetate as a solvent, and heat to 80°C using an oil bath , and allowed to react for 6 hours to obtain a prepolymer in which isocyanate groups remained. The prepolymer with residual isocyanate groups was cooled to 50°C, then dispersed into 800g of water containing 6g of potassium hydroxide under high-speed stirring, and then carried out at 50°C for 3 hours for chain extension reaction to make it reach a high molecular weight. The aforementioned ethyl acetate was recovered from the obtained aqueous liquid to obtain a substantially solvent-free polyurethane aqueous dispersion (20% by mass of polyurethane solids).
[0183] (average particle size: 170nm, film strength: 410kg / cm 2 , film elongation: 320%, film shrinkage: 1...
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