The pharmaceutical for treatment of vascular lesion through actions on the NEI network

Abstract

This invention provides drugs which are already known to be able to act effectively on informational molecules of the NET and their acceptors or influence informational molecules and their acceptors' signal transduction pathways, and their applications in preparing medicine for angiopathy treatment. The said drugs include single Chinese herbs, compound Chinese herbs and their preparations, chemical effective constituents, medicinal compounds and their preparations, biologic effective constituents, medicinal compounds and materials for their preparations. It also provides a new kind of drugs which can effectively act on the said mutual informational molecules of the NET and their acceptors, or influence their signal transduction pathways so as to treat angiopathy; and furthermore provides these drugs' preparation methods.

Description

technical field [0001] The present invention relates to a class of medicines for the treatment of vascular lesions; more specifically, to a class of information molecules (such as neurotransmitters, neuropeptides, hormones, etc.) , cytokines) and their receptors, or drugs that can affect the signal transduction pathway of shared information molecules and their receptors, thereby treating vascular diseases; and further relate to the preparation methods of these drugs. Background technique [0002] Vascular diseases such as cerebrovascular disease, cardiovascular disease, peripheral vascular disease and diabetic microvascular disease have become major diseases that seriously endanger human health. Among them, cerebrovascular disease and cardiovascular disease are the first and third diseases that cause human death, respectively. According to the "CCEP Project Implementation and Results in 2004", about 2.6 million people die of acute cardiovascular and cerebrovascular diseases ...

AI Technical Summary

Problems solved by technology

[0005] Based on the analysis of literature in recent years, although the nervous, endocrine, and immune subsystems have been discussed in the pathogenesis and prevention of vascular diseases, there is no report on the use of NEI network theory to study and prevent vascular diseases. The results of searching the Chinese Biomedical Literature Database (1978-2005) and the American Medical Literature Database (1966-2005) by the Institute of Medical Information, Chinese Academy of Medical Sciences showed that no domestic literature on the correlation between nerve, endocrine, and immune networks and vascular lesions was found. foreign literature reports