Myocardial perfusion imaging methods and compositions

a technology of myocardial perfusion and imaging methods, applied in the field of myocardial perfusion imaging methods, can solve the problems of limited use, limited usefulness of treatment with this compound, and many patients' inability to exercise at the level necessary to provide sufficient blood flow, etc., and achieve the effect of facilitating myocardial imaging
US20050020915A1Inactive Publication Date: 2005-01-27GILEAD SCI INC +1
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
GILEAD SCI INC
Publication Date
2005-01-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

A myocardial imaging method that is accomplished by administering one or more adenosine A2A adenosine receptor agonist to a human undergoing myocardial imaging as well as pharmaceutical compositions comprising at least one A2a receptor agonist, at least one liquid carrier, and at least one co-solvent.
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Description

BACKGROUND OF THE INVENTION (1) Field of the Invention This invention relates to myocardial imaging methods that are accomplished by administering doses of one or more adenosine A2A adenosine receptor agonists to a mammal undergoing myocardial imaging. This invention also relates to pharmaceutical compositions useful in myocardial imaging methods. (2) Description of the Art Myocardial perfusion imaging (MPI) is a diagnostic technique useful for the detection and characterization of coronary artery disease. Perfusion imaging uses materials such as radionuclucides to identify areas of insufficient blood flow. In MPI, blood flow is measured at rest, and the result compared with the blood flow measured during exercise on a treadmill (cardiac stress testing), such exertion being necessary to stimulate blood flow. Unfortunately, many patients are unable to exercise at levels necessary to provide sufficient blood flow, due to medical conditions such as peripheral vascular disease, arth...

Claims

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