Detection and modulation of IAPS and NAIP for the diagnosis and treatment of proliferative disease

a proliferative disease and detection technology, applied in the field of cancer diagnosis and treatment, can solve problems such as poor prognosis, and achieve the effect of enhancing apoptosis
US20060189563A1Inactive Publication Date: 2006-08-24AEGERA THERAPEUTICS INC
1 Cites 0 Cited by

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
AEGERA THERAPEUTICS INC
Publication Date
2006-08-24
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Disclosed are diagnostic and prognostic kits for the detection and treatment of proliferative diseases such as ovarian cancer, breast cancer, and lymphoma. Also disclosed are cancer therapeutics utilizing IAP antisense nucleic acids IAP fragments, and antibodies which specifically bind IAP polypeptides.
Need to check novelty before this filing date? Find Prior Art

Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This Application is a continuation application of U.S. application Ser. No. 09 / 974,592, filed Oct. 9, 2001 (now allowed), which is a continuation application of U.S. application Ser. No. 09 / 617,053, filed Jul. 14, 2000 (now U.S. Pat. No. 6,300,492), which is a continuation application of U.S. application Ser. No. 08 / 800,929, filed Feb. 13, 1997 (now U.S. Pat. No. 6,133,437).BACKGROUND OF THE INVENTION

[0002] The invention relates to the diagnosis and treatment of cancer.

[0003] One way by which cells die is referred to as apoptosis, or programmed cell death. Apoptosis often occurs as a normal part of the development and maintenance of health tissues. The process occurs so rapidly that it is difficult to detect. This may help to explain why the involvement of apoptosis in a wide spectrum of biological processes has only recently been recognized.

[0004] The apoptosis pathway is now known to play a critical role in embryonic development, v...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More