Polyurethane foams for wound management

a polyurethane foam and wound dressing technology, applied in the field of polyurethane foam for wound dressing, can solve the problems of inability to absorb physiological saline, reduced water or inconvenient handling, etc., and achieves high water and moisture vapour transmission rate, good mechanical properties, and high absorbance of physiological saline.

Inactive Publication Date: 2007-11-22
BAYER MATERIALSCIENCE AG
View PDF23 Cites 41 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0008] It has now been found that polyurethane foam forming compositions containing polyurethane dispersions and specific cationic coagulants, both free of isocyanate groups, can be used to produce at ambient conditions polyurethane foams having good mechanical properties, a high absorbenc

Problems solved by technology

The aforementioned processes, however, have the disadvantage that they require the use of reactive mixtures which contain diisocyanates or corresponding NCO-functional prepolymers, the handling of which is technically inconvenient and costly due to the necessary appropriate protective measures associated with such diisocyanates or NCO-functional prepolymers of these diisocyanates.
Polyaziridines are no longer acceptable, however, because of their toxicity.
The foams produced according to the processes described in EP 0 235 949 and EP 0 246 723, moreover, have the immense disadvantage that the foams obtained therein are only minimally open-cell, which reduces the absorbance of physiological saline and also the water or moisture vapor transmission rate.
The management of w

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Polyurethane foams for wound management
  • Polyurethane foams for wound management

Examples

Experimental program
Comparison scheme
Effect test

example 1

Polyurethane Dispersion 1

[0165] 987.0 g of Polyol 2, 375.4 g of Polyol 3, 761.3 g of Polyol 1 and 44.3 g of Polyol 4 were heated to 70° C. in a standard stirring apparatus. Then, a mixture of 237.0 g of hexamethylene diisocyanate and 313.2 g of isophorone diisocyanate was added at 70° C. over the course of 5 minutes, and the mixture was stirred at 120° C. until the theoretical NCO value was reached or the actual NCO value was slightly below the theoretical NCO value. The ready-produced prepolymer was dissolved with 4830 g of acetone and, during the process, cooled down to 50° C., and subsequently admixed with a solution of 25.1 g of ethylenediamine, 116.5 g of isophoronediamine, 61.7 g of diaminosulfonate and 1030 g of water metered in over 10 minutes. The mixture was subsequently stirred for 10 minutes. Then, a dispersion was formed by addition of 1250 g of water. This was followed by removal of the solvent by distillation under reduced pressure.

[0166] The white dispersion obtain...

example 2

Polyurethane Dispersion 2

[0167] 34.18 g of Polyol 2, 85.1 g of Polyol 3, 172.6 g of Polyol 1 and 10.0 g of Polyol 4 were heated to 70° C. in a standard stirring apparatus. Then, a mixture of 53.7 g of hexamethylene diisocyanate and 71.0 g of isophorone diisocyanate was added at 70° C. over the course of 5 minutes, and the mixture was stirred at 120° C. until the theoretical NCO value was reached or the actual NCO value was slightly below the theoretical NCO value. The ready-produced prepolymer was dissolved with 1005 g of acetone and, in the process, cooled down to 50° C. and subsequently admixed with a solution of 5.70 g of ethylenediamine, 26.4 g of isophoronediamine, 9.18 g of diaminosulfonate and 249.2 g of water metered in over 10 minutes. The mixture was subsequently stirred for 10 minutes. Then, a dispersion was formed by addition of 216 g of water. This was followed by removal of the solvent by distillation under reduced pressure.

[0168] The white dispersion obtained had th...

example 3

Polyurethane Dispersion 3

[0169] 987.0 g of Polyol 2, 375.4 g of Polyol 3, 761.3 g of Polyol 1 and 44.3 g of Polyol 4 were heated to 70° C. in a standard stirring apparatus. Then, a mixture of 237.0 g of hexamethylene diisocyanate and 313.2 g of isophorone diisocyanate was added at 70° C. over the course of 5 minutes and the mixture was stirred at 120° C. until the theoretical NCO value was reached or the actual NCO value was slightly below the theoretical NCO value. The ready-produced prepolymer was dissolved with 4830 g of acetone and, in the process, cooled down to 50° C., and subsequently admixed with a solution of 36.9 g of 1,4-diaminobutane, 116.5 g of isophoronediamine, 61.7 g of diaminosulfonate and 1076 g of water metered in over 10 minutes. The mixture was subsequently stirred for 10 minutes. Then, a dispersion was formed by addition of 1210 g of water. This was followed by removal of the solvent by distillation under reduced pressure.

[0170] The white dispersion obtained ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Fractionaaaaaaaaaa
Percent by massaaaaaaaaaa
Percent by massaaaaaaaaaa
Login to view more

Abstract

The invention relates to a process for producing polyurethane foams for wound management. These polyurethane wound dressing foams are prepared by a process comprising frothing and drying of a foam foaming composition, which comprises a polyurethane dispersion and specific coagulants.

Description

CROSS-REFERENCE TO RELATED PATENT APPLICATION [0001] The present patent application claims the right of priority under 35 U.S.C. §119 (a)-(d) of German Patent Application No. 10 2006 016 636.1, filed on Apr. 8, 2006. BACKGROUND OF THE INVENTION [0002] The present invention relates to a process for producing polyurethane wound dressing foams comprising polyurethane wound dressing foams foams which are frothed and dried, in which the polyurethane foams comprise one or more polyurethane dispersions and one or more coagulants. [0003] Polyurethane wound dressing foams are known to be suitable for treating exsudating wounds. Due to their high absorbency and their good mechanical properties, polyurethane foams produced by reaction of mixtures of diisocyanates and polyols or NCO-functional polyurethane prepolymers with water in the presence of certain catalysts and also (foam) additives are generally used. Aromatic diisocyanates are generally employed. Numerous forms of these processes for ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61F15/00C08G18/00
CPCA61L15/26A61L15/425Y10S514/945C08L75/04A61P17/02A61L15/42
Inventor RISCHE, THORSTENMAGER, MICHAELHECKES, MICHAELRUDHARDT, DANIELGERTZMANN, ROLFDIETZE, MELITAFUGMANN, BURKHARD
Owner BAYER MATERIALSCIENCE AG
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap