Pharmaceutical composition for preventing or treating neuronal damage and neurological diseases
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example 1
Preparation of H-Z Cream
[0052]0.7 g of potassium hydroxide and 10 mL of glycerin were dissolved in 75 mL of purified water in a 200 mL beaker and then the solution was heated at a temperature of 80 to 85° C. This solution was added to a liquid stearic acid prepared by completely melting 15 g of stearic acid in a 250 mL beaker in a water bath at a temperature of 80 to 85° C. and stirred and cooled to room temperature, thereby preparing a vanishing cream.
[0053]100.7 g of the prepared vanishing cream was added to 229.0 g of aloe vera gel and the mixture was sufficiently mixed. Then, 16.03 g of Oronia Soybean Lecithin (supplier: Deraco Natural Source Company LTD.) as a phospholipid or sphingosine derivative, 1.60 g of alpha-tocopherol, and 0.50 g of propyl benzoate were each added thereto in small portions while stirring, thereby preparing a light yellowish cream. The resultant composition included 1.7 wt % of phospholipid or a sphingosine derivative.
example 2
Preparation of H-Z Cream
[0054]4.00 g of Tween #80 was added to 200.0 g of aloe vera gel and the mixture was sufficiently mixed. Then, 20.00 g of Oronia Soybean Lecithin (supplier: Deraco Natural Source Company LTD.), 2.00 g of alpha-tocopherol, and 0.30 g of propyl benzoate were each added thereto in small portions while stirring, thereby preparing a light yellowish cream. The resultant composition included 3.24 wt % of phospholipid or a sphingosine derivative.
example 3
Preparation of H-Z Cream
[0055]14.00 g of Tween #80 was added to 127.0 g of aloe vera gel and the mixture was sufficiently mixed. Then, 70.00 g of GL-90E (supplier: GoshenBiotech) as phospholipid or a sphingosine derivative, 7.00 g of alpha-tocopherol, and 0.30 g of propyl benzoate were each added thereto in small portions while stirring, thereby preparing a light yellowish cream. The resultant composition included 29.1 wt % phospholipid or a sphingosine derivative.
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