Handheld molecular imaging navigation system

Abstract

A handheld molecular imaging navigation system comprises a multi-spectral light source module configured to provide light in a plurality of different spectrum bands in a time division control manner according to a control signal sequence to irradiate an inspected object; a time division control module configured to generate the control signal sequence; an optical signal acquisition module configured to acquire a near-infrared fluorescence image and a visible light image of the inspected object in a time division control manner according to the control signal sequence provided by the time division control module; and a processing module configured to perform image processing on the acquired near-infrared fluorescence image and visible light image according to the control signal sequence to fuse the visible light image and the fluorescence image and output the fused image, and output a feedback signal according to the acquired near-infrared fluorescence image and visible light image.

Description

TECHNICAL FIELD[0001]The present disclosure relates to imaging systems, and more particularly to a handheld molecular imaging navigation system.BACKGROUND[0002]As a new method and means of the noninvasive visual imaging technology, molecular imaging reflects essentially changes in the physiological and molecular level of organisms and changes in the overall functionality caused by changes in molecular regulation. Therefore, it is an important technique to study life activities of genes, bio-macromolecules and cells in vivo at the molecular level, wherein the basic research of the physiological optical imaging technology in vivo based on molecular technology, tomography, optical imaging technology, and simulation methodology has become one of the hot and difficult spots of research in the molecular imaging field.[0003]Molecular imaging devices combine traditional medical imaging technology with modern molecular biology to observe physiological or pathological changes at cell and mole...

AI Technical Summary

Benefits of technology

[0026]first of all, due to the use of handheld device to acquire images, in the process of biomedical applications, the operation can be simplified, and the application scope can be expanded; and

[0027]secondly, due to the use of the time division control method, multi-spectral real-time imaging is achieved by image acquisition and image processing. In addition, by setting the multi-spectral switchers and the time division control module, the multi-spectral light source module is switched to cooperate with timing control, which makes it possible to effectively achieve molecular imaging navigation, maximize detected light intensity, and effectively retain useful information. In practical operations, not only strong fluorescence information can be seen, but also visible light information can be seen by an observer, without influences between light in two spectrums.

Problems solved by technology

Therefore, it is an important technique to study life activities of genes, bio-macromolecules and cells in vivo at the molecular level, wherein the basic research of the physiological optical imaging technology in vivo based on molecular technology, tomography, optical imaging technology, and simulation methodology has become one of the hot and difficult spots of research in the molecular imaging field.

However, the system using this method is relatively complex, and the ease of operation and the comfort of use need to be further improved.

Images