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9results about How to "Improve induction ability" patented technology

Prison break attack method and device for Chinese large model, and electronic equipment

PendingCN119441441AIncrease attack effectImprove induction abilityDigital data information retrievalInternal combustion piston enginesAlgorithmAttack
The invention relates to the technical field of generative large models, and discloses a jailbreak attack method for a Chinese large model, which comprises the following steps: performing data enhancement on an attack problem to be input; splicing the enhanced attack problem with the selected attack template; taking the spliced data as the input of a test model, attacking the test model, and obtaining the output of the test model; wherein the test model is a Chinese large model; and judging whether the output of the test model is safe or not according to the constructed safety evaluation model so as to count the attack success rate. The method can adapt to a Chinese attack scene, and the Chinese induction capability is improved. And the attack validity can be quantified by counting the attack success rate. The invention further discloses a jailbreak attack device for the Chinese large model and electronic equipment.
Owner:CHINA ACADEMY OF INFORMATION & COMM

High-strength silk fibroin / hydroxyapatite bone repair material and preparation method thereof

The invention discloses a high-strength silk fibroin / hydroxyapatite bone repair material and a preparation method thereof, and belongs to the field of biomedical materials. Methacrylic acid esterified silk fibroin and methacrylic acid esterified nano-hydroxyapatite are used as organic matter and inorganic filler, and the interface bonding capacity and dispersion stability between the organic component silk fibroin and the inorganic component hydroxyapatite are improved through photo-crosslinking; and performing high-temperature hot-pressing molding to obtain the silk fibroin / hydroxyapatite bone repair material. The bone repair material has relatively strong mechanical properties, osteogenesis induction capability, good biocompatibility and degradability, and has a wide application prospect in the field of bone defect repair.
Owner:FUZHOU UNIV

Vanadium-doped mesoporous bioactive glass powder for treating diabetic wounds and preparation method of vanadium-doped mesoporous bioactive glass powder

PendingCN121929898AEffectively maintain simulation activityHigh biosecurityPlastersGlass shaping apparatusBioactive glassPhysical chemistry
The invention relates to the technical field of biological material manufacturing, in particular to vanadium-doped mesoporous bioactive glass powder for treating diabetic wounds and a preparation method of the vanadium-doped mesoporous bioactive glass powder. Adding an ammonia solution into the template agent solution to obtain a mixed solution; adding a silicon source, a phosphorus source, a calcium source and a vanadium source into the mixed solution in batches according to a preset interval time under a continuous stirring condition, continuously stirring and reacting for 5.5-24 hours, and centrifuging and collecting a precipitation product; and washing, roasting and grinding the obtained precipitation product to obtain the vanadium-doped mesoporous bioactive glass powder for treating diabetic wounds.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

A chimeric polypeptide, related biomaterials and their application in induced cardiomyocytes

ActiveCN121591917BAmazing transcriptional activityImprove induction efficiencyAntibody mimetics/scaffoldsGenetically modified cellsGATA6Mef2
This invention belongs to the field of biomedicine and regenerative medicine technology. It discloses a chimeric polypeptide, related biomaterials, and their application in inducing cardiomyocytes. The chimeric polypeptide is obtained through family homologous domain substitution and is selected from the following groups: (1) a MEF2 chimeric polypeptide with MEF2C protein as the backbone, wherein the N-terminal and C-terminal transcriptional activation domains are replaced by homologous regions of MEF2B and MEF2D, respectively; (2) a GATA chimeric polypeptide with GATA4 protein as the backbone, wherein the N-terminal transcriptional activation domain is replaced by homologous regions of GATA1 and GATA6. This invention also provides the nucleic acid encoding the polypeptide, the construct, and a method for efficiently inducing fibroblast reprogramming into cardiomyocytes under in vitro conditions. When the chimeric polypeptide of this invention is used alone or in combination, the induced cells exhibit calcium ion oscillations earlier and have higher maturity.
Owner:GUANGZHOU MEDICAL UNIV

Application of Dendrobium nobile in the preparation of breast cancer treatment drugs and breast cancer treatment drugs

PendingCN122075453AInhibition of activityInhibition of clonogenicityEther/acetal active ingredientsSexual disorderWestern blotPharmaceutical drug
This invention relates to the field of breast cancer therapeutics, providing a novel application of *Dendrobium nobile*, specifically the application of dendrobine in the preparation of breast cancer therapeutics. This invention verifies that dendrobine can significantly inhibit breast cancer cell viability. The inhibitory effect of dendrobine on the migration and proliferation of T47D breast cancer cells and its ability to induce cell death increases with increasing dosage. Simultaneously, cloning experiments also show that dendrobine significantly inhibits the colony-forming ability of breast cancer cells. ROS and JC-1 experiments also show that dendrobine induces mitochondrial dysfunction and increases ROS levels. Western blot experiments show that under dendrobine treatment, the expression levels of ferroptosis markers GPX4 and Nrf2 are significantly reduced. Dendrobine can promote ferroptosis in breast cancer cells and inhibit their cell viability by inducing mitochondrial dysfunction, and it holds promise as a breast cancer therapeutic drug specifically targeting ferroptosis.
Owner:SOUTHWEST MEDICAL UNIV

Arrow induction lamp in tunnel

The utility model relates to the technical field of induction lamps, and discloses an arrow induction lamp in a tunnel, which comprises a lamp panel body, a controller is connected to the back of the lamp panel body, a plurality of arrow lamps are arranged at the upper end of the front of the lamp panel body, the arrow lamps form an indicating arrow, and the indicating arrow is lighted in sequence from the arrow tail to the arrow end. An electronic screen is fixedly arranged at the lower end of the front face of the lamp panel body, and curve vehicle conditions are displayed on the electronic screen. The tunnel curve display device has the advantages of being multifunctional, good in tunnel curve display effect and capable of reducing the occurrence probability of accidents.
Owner:SHANDONG RUIHENG OPTOELECTRONICS TECH CO LTD

Efficient adhesion type insect trapper

The utility model discloses an efficient adhesion type insect trapper, and relates to the technical field of insect trapping, the efficient adhesion type insect trapper comprises a supporting plate, four photovoltaic power generation devices are installed on the periphery of the top of the supporting plate, four insertion grooves are formed in the periphery of the interior of the supporting plate, and the photovoltaic power generation devices are inserted into the insertion grooves. Two magnetic suction plates are installed on the two sides of the top of the insertion groove. An adhesion assembly is slidably connected to the interior of the insertion groove and comprises an insertion plate, the insertion plate is slidably connected to the interior of the insertion groove, an iron plate is installed at the top of the insertion plate, a grip is installed at the top of the iron plate, and a connecting plate is installed at the bottom of the insertion plate; and two pieces of second adhesive paper are mounted on the two sides of the connecting plate. According to the insect catching device, the adhesion assembly and the supporting assembly are used in cooperation, so that the insect catching effect is improved through the arrangement of the first adhesive paper and the second adhesive paper, and the first adhesive paper and the second adhesive paper can be conveniently and rapidly replaced.
Owner:SHENZHEN BAILEFU ELECTRONIC TECH CO LTD

Rapid seedling raising method for euphorbia filiformis

PendingCN119256981AImprove induction abilityImprovement factorAfforestationPlant tissue cultureEuphorbiaEuphorbia francoisii
The invention belongs to the technical field of euphorbia filiformis seedling culture, and particularly relates to a rapid seedling culture method of euphorbia filiformis, which comprises the following steps: explant sterilization treatment, callus induction, callus differentiation, strong seedling culture, acclimatization and transplantation and transplantation management. According to the method, tender leaves of euphorbia filiformis are selected as explants, rapid seedling culture of euphorbia filiformis is carried out on the explants through the steps of callus induction, callus differentiation, strong seedling culture, seedling hardening and the like, and an induction culture medium, a differential culture medium, a strong seedling culture medium and the like in the seedling culture process are optimized and improved. The induction effect, growth coefficient and rooting rate of calluses can be improved, cultivated seedlings can be robust and grow well, the purposes of effectively controlling the production cost and rapidly producing seedlings are achieved, and a foundation can be laid for large-scale production of euphorbia filiformis.
Owner:GUANGXI ZHUANG AUTONOMOUS REGION ACAD OF AGRI SCI

Recombinant protein VP8: CTB for inducing long-acting rotavirus neutralizing antibody and application thereof

The invention discloses a recombinant protein VP8: CTB for inducing a long-acting rotavirus neutralizing antibody and application of the recombinant protein VP8: CTB. According to the present invention, the soluble expression of the CTB-Spycater003 carrier protein and the VP8-Spytag003 protein is achieved, and the rotavirus recombinant subunit vaccine is assembled through the in vitro coupling; the recombinant subunit vaccine has intact antigenicity and immunogenicity, and can induce mice to generate long-acting and high-titer IgG binding antibodies and broad-spectrum neutralizing antibodies.
Owner:SHANGHAI INSTITUTE OF INFECTIOUS DISEASE & BIOSECURITY