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Featherleaf rodgersflower and pyrola herb contained tablet for treating mammary disease and preparation processthereof

A technology of Yantuo and lactose, which is applied in the field of pharmaceutical preparations, Yanlurukang Tablets and its preparation, can solve the problems of single dosage forms and application dosage forms that cannot meet clinical medication requirements, and achieve easy acceptance, enrich clinical dosage forms, and meet clinical medication requirements. effect of demand

Inactive Publication Date: 2007-10-17
石药集团中诺药业(石家庄)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The original dosage form of Yanlurukang is only capsules, which is a single dosage form, and the application dosage form cannot meet the needs of clinical medication

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] (1) Preparation of rock deer extract powder

[0018] 1. In the prescription (calculated as 1000 tablets), 445g of Yantuo, 62.5g of Luniancao, and 7.5g of Antler Cream are tested and qualified respectively for later use; Yantuo and ethanol are refluxed three times, each for 2 hours for the first time, and for the second and second. Three times for 1 hour each, combine the extracts, filter, recover ethanol from the filtrate and concentrate to a clear paste with a relative density of 1.15-1.25 (50°C-55°C), and set aside;

[0019] 2. Separately take the deer's grass and the deer's horn cream to be crushed separately, and passed through a 100-mesh sieve;

[0020] 3. Mix the drugs obtained in the steps 1 and 2 evenly, dry, pulverize, and pass through a 100-mesh sieve to obtain 233 g of rock deer extract powder.

[0021] (2) Preparation of Yanlu Rukang Tablets

[0022] Components:

[0023] Yanlu Extract Powder 233g

[0024] Microcrystalline Cellulose 50g

[0025] Starch 7...

Embodiment 2

[0033] (1) The preparation of rock deer extract powder is the same as in Example 1.

[0034] (2) Preparation of Yanlu Rukang Tablets

[0035] Components:

[0036] Yanlu Extract Powder 233g

[0037] 45g powdered sugar

[0038] Glucose 20g

[0039] Mannitol 37g

[0040] Dextrin 47g

[0041] Sodium carboxymethyl starch 8g

[0042] 5% ethanol solution of PVP appropriate amount

[0043] Talc powder 7.2g

[0044] Magnesium Stearate 2.8g

[0045] Preparation:

[0046] 1. Mix 233g of Yanlu extract powder, 40g of powdered sugar, 20g of glucose, and 38g of mannitol, use 5% PVP ethanol solution as a binder, make granules, dry, and granulate with 40 mesh; add 7.2 talcum powder g, magnesium stearate 2.8g, mixing; Tablets are made with a tablet machine, and each tablet weighs 0.4g, and the gastric-soluble material premix Oubadiene of Colorcon Company is used as the film coating material, and the tablet is prepared Film coated.

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PUM

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Abstract

The invention provides a featherleaf rodgersflower and pyrola herb tablet which is prepared from extract powder extracted from 400-500 parts of Yantuo, Chinese pyrola herb 55-65, deglued antler powder 5-10 and balancing tabletting adjuvant. The preparing process comprises the following steps, (1) subjecting Yantao 445 to ethanol backflow, merging the extracts, filtrating, reclaiming ethanol from the filtrate, concentrating to obtain clear grease with a specific gravity of 1.15-1.25, (2) disintegrating herba pyrolae 62.5, deerhorn cream 7.5, passing through 100 mesh sieve, (3) mixing herba pyrolae, deerhorn cream with Yantao clear cream, charging auxiliary materials, bed blending, obtaining granules, drying, granulating and tabletting.

Description

technical field [0001] The invention relates to a Yanlurukang tablet and a preparation method thereof, belonging to the technical field of pharmaceutical preparation methods. Background technique [0002] The original dosage form of Yanlurukang is only capsules, which is a single dosage form, and the application dosage form cannot meet the needs of clinical medication. Contents of the invention [0003] The technical problem to be solved by the present invention is that we use modern pharmaceutical technology to improve the production process and dosage form of this product, and make it into a tablet or film-coated tablet that is easy to carry and use, and has stable quality, so as to enrich the clinical dosage form and facilitate people to use it. . [0004] The technical solution of the present invention is achieved in this way: Yanlu Rukang Tablets, characterized in that: it is the extract powder extracted from Yantuo 400-500 of the following parts by weight, 55-65 of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61K35/32A61K9/20A61K9/28
Inventor 梁纪军李勇郭惠娟康丽霞
Owner 石药集团中诺药业(石家庄)有限公司
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