Use of biological keratin for pharmaceutical preparation
A technology of keratin and products, applied in the field of natural biomaterial keratin in the pharmaceutical field, to achieve the effect of regulating blood vessel proliferation, convenient transportation, and enriching tissue nutrition
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Embodiment 1
[0024] Embodiment 1: Animal experiment of BK promoting wound surface repairing agent on wound surface repair of skin damage
[0025] Select 20 Japanese white rabbits, weighing 2.5-3.0kg, male or female. Depilate, anesthetized with 3% pentobarbital sodium, and make 2 wounds on both sides of the spine of each rabbit, totally 4 parallel wounds of 2cm×2cm full-thickness skin lesions (sarcolemma preserved). Mark them as A, B, C, and D in turn, and the 20 wounds of A, B, C, and D corresponding to 20 rabbits are named in turn as group A, group B, group C, and group D, and they are respectively applied to liquid-phase activation of this product. BK Wound Repair Agent, Beifuji Liquid, Kangfuxin Liquid and normal saline were used to wet compress the wound, and the wound was covered and fixed with vaseline oil gauze to prevent dryness, and the dressing was changed twice a day. Use 1mm for each square when observing 2 The gauze covered the wound, and the wound healing area was calculate...
Embodiment 2
[0033] Example 2: Clinical Observation of BK Accelerating Wound Repair Agent in Treating Large Area Deep II Degree Burns
[0034] There were 12 patients with deep second-degree burns, including 7 males and 5 females. The total burn area was greater than 50%, and the average deep second-degree burn area was 53.5±3.8%. They were randomly divided into observation group (53.7%±3.5% deep second-degree burn area) and 6 cases in control group (53.1%±4.1% deep second-degree burn area). Both groups were treated with fluid-suspended beds, and sensitive antibiotics were infused intravenously. After debridement in the observation group, take the BK wound-promoting repair mesh with a suitable area of the solid-phase activator of this product and spread it on the wound surface, and then spray the liquid-phase BK wound-promoting repair agent directly on the wound surface and cover it with vaseline gauze to prevent water from evaporating. . Once a day, until the film was formed; the cont...
Embodiment 3
[0040] Example 3: Clinical observation of BK promoting wound repair agent in the treatment of contusion wounds
[0041] Fourteen patients with contusion were randomly divided into two groups, including 7 cases in the observation group, 5 males and 2 females. Injury site: 6 cases of lower limbs, 1 case of upper limbs; 7 cases of control group, 4 cases of male and 3 cases of female. Injury sites: 5 cases of lower limbs, 2 cases of upper limbs. Both groups had no diabetes or blood diseases. The observation group performed debridement on the injured wound to remove dirt and foreign matter on the wound, and then soaked it twice with 0.05% iodophor disinfectant for 3 to 5 minutes each time, washed away the disinfectant on the wound with sterile saline, and performed routine disinfection. Skin, according to aseptic operation, cut off necrotic tissue, keep the wound fresh, dry the blood with sterile gauze, evenly spray the liquid phase activator BK wound repair agent on the affected...
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