Rotary platform type animals in-vivo multi-mode imaging detection system

Abstract

The invention relates to a biological multimode picture detecting technique, wherein it comprises one PET shooting system with symmetry electrodes, one infrared transparent (reflective) shooting system, one visual light (or fluorescent) transparent (or reflective) shooting system, one ultraviolet (or X-ray) transparent (or reflective) shooting system, one rotation carrier of animal, multi-axle motion controller, multi-channel processor and computer. The carrier comprises one object platform, one frame, one constant-temperature controller, one rotator, and one XYZ three-dimension mover. The invention has multimode composition and 360degree scanning picture, with low cost.

Description

technical field [0001] The invention relates to small animal in vivo imaging detection technology and scientific instrument device structure, in particular to provide a small animal molecular imaging detection system and platform structure with flexible structure, low cost, and relatively high detection sensitivity and resolution. Background technique [0002] In vivo molecular imaging detection of small animals is a key link in systems biology research, and it is also an intermediate bridge between scientific research explorations such as gene protein molecular level detection and cellular level detection to clinical detection applications. Nearly 100 related articles have reported the research results in this area. To carry out research work in this area, two types of instruments are inseparable. One is PET detection instruments, and the price of foreign products is more than 3 million → 5 million yuan; the other is Xenogen's small animal in vivo visible light fluorescence...

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Problems solved by technology

The second is the detector, which is the core component of in vivo molecular image detection of small animals. At present, foreign high-sensitivity low-temperature refrigeration CCD detectors range from tens of thousands to hundreds of thousands of dollars, and only 3 foreign companies have mature products. ; The key issue in the third aspect is the optical system structure and lens. High-quality optical lenses with large numerical aperture and long working distance range from several thousand to more than ten thousand dollars. If you need to customize with a specific optical imaging system, a complete set Optical systems and lenses cost tens of thousands of dollars and are monopolized by Zeiss, Nikon and Leica

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