Novel use of silver peroxide

A technology of silver peroxide and medicine, which is applied in the field of chemical compounds, can solve the problems of low valence and unreliable curative effect, and achieve the effects of stable performance, high cost performance and high bactericidal efficiency

Inactive Publication Date: 2009-12-23
SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, due to the low valence state of metallic silver or silver oxide, its efficacy as an active ingredient in medicines for the treatment of gynecological diseases and superficial skin fungal infections needs to be improved.

Method used

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  • Novel use of silver peroxide
  • Novel use of silver peroxide
  • Novel use of silver peroxide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1, the preparation of silver peroxide

[0020] The preparation method of silver peroxide is as follows: (1) get 25% sodium persulfate (NaS 2 o 8 ) solution 400 milliliters; (2) put into the sodium persulfate solution the stirrer that the lower end has been installed with silver stirring blade, stir 4~7 hours in dark place, obtain black silver peroxide precipitate, its reaction formula is: 2Ag+2NaS 2 o 8 +2H 2 O=Ag 2 o 2 +2Na 2 SO 4 +2H 2 SO 4 (3) filtering, washing and drying the silver peroxide precipitate to obtain dry silver peroxide. Silver peroxide molecule (Ag 2 o 2 ) consists of a trivalent silver ion and a monovalent silver ion.

[0021] Commercially available silver peroxide compounds can also be used.

Embodiment 2

[0022] Embodiment 2, the preparation of silver peroxide tablet

[0023] The following ingredients were mixed and prepared into 1000 tablets each containing 5 mg of silver peroxide.

[0024] Silver peroxide 5g

[0025] Microcrystalline Cellulose 137g

[0026] Mannitol 30g

[0027] Polyvinylpyrrolidone K30 26g

[0028] Magnesium Stearate 2g

[0029] Total 200g

[0030] Silver peroxide is sieved and mixed with microcrystalline cellulose and mannitol to form a uniform mixture; granulated with polyvinylpyrrolidone K30 aqueous solution and passed through a 16-mesh sieve; after drying, granulated and mixed with magnesium stearate and the resulting granules are then compressed into tablets. Tablets with other contents can be prepared by changing the ratio of active compound and excipients or the tablet weight.

Embodiment 3

[0031] Embodiment 3, the preparation of silver peroxide ointment

[0032] The following ingredients were mixed in a conventional manner to obtain an ointment containing 1% by weight of silver peroxide.

[0033] Silver peroxide 1g

[0034] olive oil 10g

[0035] White Vaseline 89g

[0036] Total 100g

[0037] Disperse the silver peroxide in the olive oil, add it into the melted white vaseline under stirring, mix well and fill it.

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PUM

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Abstract

The invention discloses a new application of silver peroxide, that is, the application of silver peroxide in the preparation of medicines for preventing and treating women's reproductive tract infection and superficial skin fungal infection. The composition of the medicine comprises silver peroxide as an active ingredient, a pharmaceutically acceptable carrier and a medical auxiliary or excipient. In addition, the invention also provides a preparation method of medicines in different dosage forms for preventing and treating women's reproductive tract infection and superficial skin fungal infection with silver peroxide as the active ingredient.

Description

technical field [0001] The present invention relates to the new application of compound, especially relates to the new application of silver peroxide. Background technique [0002] Metallic silver or silver oxide has been used as an active ingredient in drugs for the treatment of gynecological diseases and superficial fungal infections of the skin. For example, Chinese patent CN 1241662A discloses a nano-silver long-acting broad-spectrum antibacterial functional fabric, with ultra-fine silver attached between or on the fibers of the fabric, the surface layer of ultra-fine silver is silver oxide, and the core is metallic silver , the fabric can treat superficial fungal infections of the skin. Chinese patent CN 1328819A discloses a nano-silver antibacterial and anti-inflammatory film for gynecological diseases, which contains pharmaceutically acceptable additives and anti-aggregation broad-spectrum antibacterial nano-silver powder. The surface layer is silver oxide and the co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/38A61P15/02A61P17/00A61P31/10A61P33/02
Inventor 郑荣宇兰平罗小明蒋华德孙勇韩碧顺邱冬招
Owner SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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