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Medicament for treating chronic kidney disease proteinuria and preparation thereof

A technology for chronic kidney disease and proteinuria, which is applied in the preparation of the drug and in the field of traditional Chinese medicine preparations for the treatment of kidney disease, to reduce pathological changes, improve blood rheology indicators, and increase plasma albumin.

Inactive Publication Date: 2010-03-24
FIRST HOSPITAL OF SHANXI MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Some recognized drugs currently used to control proteinuria, such as ACEIs, ARBs, glucocorticoids, and immunosuppressants, have certain limitations in clinical use.

Method used

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  • Medicament for treating chronic kidney disease proteinuria and preparation thereof
  • Medicament for treating chronic kidney disease proteinuria and preparation thereof
  • Medicament for treating chronic kidney disease proteinuria and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Take 100Kg of astragalus, 75Kg of Alisma, 50Kg of schisandra, 75Kg of Gorgon, and 150Kg of lotus root, put them into an extraction tank, add 500Kg of water, decoct for 2 hours, filter out the decoction, add the same amount of water, and decoct twice, each time 2h. Combine 3 decoctions, filter, concentrate to a thick paste with relative density of 1.20-1.24, dry and pulverize into 80-mesh fine powder, put into capsules, sterilize and make capsule products.

Embodiment 2

[0044] Take 150Kg of astragalus, 50Kg of Alisma, 40Kg of schisandra, 50Kg of Gorgon, and 100Kg of lotus root joints, put them into an extraction tank, add 500Kg of water, decoct for 2 hours, filter out the decoction, add the same amount of water, and decoct twice, each time 2h. Combine 3 decoctions, filter, concentrate to a thick paste with relative density of 1.20-1.24, dry and pulverize into 80-mesh fine powder, put into capsules, sterilize and make capsule products.

Embodiment 3

[0046] Take 80Kg of astragalus, 75Kg of Alisma, 60Kg of schisandra, 75Kg of Gorgon, and 200Kg of lotus root, put them into the extraction tank, add 500Kg of water, decoct for 2 hours, filter out the decoction, add the same amount of water, and decoct twice, each time 2h. Combine 3 decoctions, filter, concentrate to a thick paste with relative density of 1.20-1.24, dry and pulverize into 80-mesh fine powder, put into capsules, sterilize and make capsule products.

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Abstract

The invention relates to a drug for treating chronic kidney disease proteinuria, which is a capsule prepared as follows: the materials are astragalus, Oriental Waterplantain Rhizome, Chinese Magnolivine Fruit, fried foxnut and node of lotus rhizome, which are added to water to be decocted, and the decoction solution is concentrated and dried. The drug has the advantages of kidney invigorating, diuresis inducing and stranguria treating, blood activating and stasis removing, swelling reducing and pain alleviating, heat-clearing and detoxifying, body fluid regenerating and thirst quenching, darrhea relieving, cough relieving and bleeding stopping, which has the function of body immunity regulation and reinforcing, and is suitable for the patient with chronic kidney disease and chronic renal failure proteinuria; the drug can effectively reduce proteinuria, increase plasma albumin, reduce the pathological changes of kidney and improve hemorheology indexes, which has a certain controlling effect on hematuria and proteinuria. In clinical verification, the drug has the advantages of fast therapeutic effect, good efficacy and small side effect.

Description

technical field [0001] The invention relates to a medicine, in particular to a traditional Chinese medicine preparation for treating nephropathy, and also relates to a preparation method of the medicine. Background technique [0002] Chronic kidney disease is a common disease in clinical practice, but it is easily overlooked due to the inconspicuous early symptoms. About 20% of patients with kidney disease are often at an advanced stage when they first come to the hospital for treatment due to lack of awareness of the prevention and treatment of kidney disease. In addition, patients with chronic kidney disease are prone to various complications, such as the incidence of cardiovascular disease is dozens of times higher than that of normal people, and it can also cause anemia, bone disease, malnutrition, and decreased sexual function. If the prevention and treatment of chronic kidney disease are not paid attention to in the early stage, it will develop progressively, leading ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/884A61K36/62A61K36/57A61K36/481A61K9/48A61P13/12
Inventor 方敬爱孙艳艳刘文媛常沁涛王蕊花范彦君李慧王月香张晓东孙桂枝
Owner FIRST HOSPITAL OF SHANXI MEDICAL UNIV
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