Ginkgo leaves purified lyophiled powder preparing technique

Abstract

The invention relates to a preparing process for folium ginkgo purifying freeze dried powder, characterized that: ginkgoic acid as an injurious ingredient can be effectively removed from the folium ginkgo by a supercritical CO2 extraction technology replacing traditional alcohol extraction; the product has stronger efficacy by the fact that it is much easer to preserve bioactive component of the folium ginkgo by extracting in low temperature of 35-40 DEG C. than that in high temperature of 65-75 DEG C; bioactive damage of the product during drying is close to zero by vacuum freeze drying process in temperature of -40 DEG C. rather than traditional spray drying process in 150 DEG C; due to a separation and purification process of biomembrane method and chromatography, purity of the product is greatly improved compared with the traditional product, the content of ginkgo flavone and lactone as active ingredient is more than 50%, and injurious ingredient is further reduced, so that the content of the ginkgoic acid is less than 5ppm.

Description

technical field [0001] The invention relates to a preparation process of ginkgo leaf purified freeze-dried powder, which can be used as a raw material of biological products and belongs to the field of biotechnology. Background technique [0002] The traditional ginkgo leaf production process is to dry the purchased ginkgo leaf raw materials at a high temperature of 105°C, and then extract them with 55% to 65% alcohol solution. The extraction temperature is generally controlled between 65°C and 75°C. The liquid ratio is generally controlled within the range of 1:3.3 to 1:2.5; extract for two hours, then filter, concentrate, and spray dry at high temperature to make a powder product. [0003] This processing method has the following disadvantages: [0004] 1. High-temperature drying during processing will inactivate the bioactive components in Ginkgo biloba leaves, resulting in reduced or even lost efficacy of the product; [0005] 2. The extraction efficiency of the alcoho...

AI Technical Summary

Problems solved by technology

[0004] 1. High-temperature drying during processing will inactivate the bioactive components in Ginkgo biloba leaves, resulting in reduced or even lost efficacy of the product;

[0005] 2. The extraction efficiency of the alcohol extraction process is low; the yield of the product is generally only between 3% and 5%, resulting in a great waste of resources;

[0007] 4. The content of harmful substances in the product is high; the content of gingkgo acid is greater than 5ppm, which is a strong allergen and can cause great damage to the human nervous system;

[0008] 5. The production energy consumption is high, and the solvent consumption is large; boilers, drying rooms, and alcohol recovery systems are required, and the steam consumption is large;

[0009] 6. The pollution to the environment is relatively large, and a large amount of waste needs to be disposed of