Function of anemarrhena extract for preparing medicine of treating prostatic hyperplasia

A technology of anemarrhena extract and benign prostatic hyperplasia, which is applied in the field of medicine, can solve problems such as anemarrhena anemarrhena extract benign prostatic hyperplasia, and achieve the effect of strong pharmacological effect, low price, and simple preparation process

Inactive Publication Date: 2007-10-31
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] But so far there is no report about the use of Anemarrhena extracts for the treatment of benign prostatic hyperplasia

Method used

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  • Function of anemarrhena extract for preparing medicine of treating prostatic hyperplasia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: Anemarrhena anemarrhena extract preparation

[0035]Put 100 kg of pulverized Anemarrhena medicinal materials into the extraction tank, heat and extract 3 times with 400 liters of 70% ethanol at 90-100 ℃, each extraction time is 90 minutes, combine the 3 extractions, concentrate to 80 liters, and filter , the filtrate was adjusted to 100 liters with distilled water. Slowly pass through an adsorption column with 350 liters of ZTC-1 type macroporous resin (produced by Tianjin Zhengtiancheng Clarification Technology Co., Ltd.), and rinse out impurities with 500 liters of distilled water; Liquid, concentrated to 10 liters, left standing for 24 hours, precipitated, filtered, dried and crushed to obtain 0.4 kg of light yellow precipitate, which is extract 1; then slowly add 100 liters of 95% ethanol to the filtrate under stirring, and stand for 12 hours, centrifuged, and the precipitation supernatant was concentrated to dryness, dried and pulverized to obtain 1....

Embodiment 2

[0036] Embodiment 2: pharmacological activity test

[0037] experiment material:

[0038] 1. Animal: SD rat, provided by Shanghai Slack Experimental Animal Co., Ltd., clean grade (animal certificate number SCXK (Shanghai) 2002-0010)

[0039] 2. Drugs: Anemarrhena extracts were prepared according to the specific preparation method in Example 1.

[0040] 3. Reagent: Testosterone Propionate Injection (Shanghai General Pharmaceutical Co., Ltd., 1ml / bottle, batch number: Guoyao Zhunzi H31020524)

[0041] Method and Results:

[0042] method:

[0043] 1) Animal treatment: The animal model was built with reference to the part of the test method above. The SD rats were randomly divided into groups (10 rats in each group): anemarrhena extract administration group, model control group and blank control group. Except the blank group, each rat in the other groups was subcutaneously injected with testosterone propionate injection 3 mg / (kg·d), and the normal control group was subcutaneo...

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PUM

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Abstract

The invention discloses an application of compound of timosaponin extract in foods and preparation of prostate hyperplasia medicine in medicine and pharmacology technical domain, which is characterized by the following: possessing saponin and chromocor chemical element in timosaponin; possessing anti-diabetes medicinal and antibiotic function; setting the sum of mango glycosides and new mango glycosides content not less than 50%. This invention also discloses a basic preparing method. This invention can be used to cure big mouse prostate hyperplasia of enarmon, which can prepare medicine to prevent and cure prostate hyperplasia.

Description

Technical field: [0001] The invention relates to the technical field of medicine, in particular to the application of an anemarrhena extract in preparing medicine or food for preventing and treating prostatic hyperplasia. Background technique: [0002] Zhimu is the rhizome of Anemarrhena asphodeloides Bunge, a plant of the Liliaceae family. It has the effects of nourishing yin and reducing fire, moisturizing dryness and smoothing the intestines. It is mostly used clinically for diabetes. At present, Anemarrhena anemarrhena is mainly used as a unit of decoction pieces or decocted with other traditional Chinese medicines. [0003] The chemical components of Anemarrhena are mainly saponins and flavonoids: [0004] Wherein the reported flavonoid components mainly include: baohuoside-I, icariin-I, mangiferin, isomangiferin and neomangiferin (1. Journal of Shenyang Pharmaceutical University, 1995, 13 (1): 34 2. Journal of Shenyang Pharmaceutical College, 1993, 10(2): 141; Natura...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P13/08A61K125/00
Inventor 陈万生孙赫孙连娜李铁军
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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