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Simulation system of function of biological organ

A functional simulation, biological technology, applied in the field of simulation system

Inactive Publication Date: 2011-02-09
SYSMEX CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method can predict the blood sugar level, but cannot understand the status of the organs related to blood sugar control

Method used

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  • Simulation system of function of biological organ
  • Simulation system of function of biological organ
  • Simulation system of function of biological organ

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Experimental program
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Embodiment Construction

[0070] The CPU 110a can execute computer programs stored in the ROM 110b and computer programs loaded by the RAM 110c. When this CPU 110 a executes an application program 140 a described later, each functional module described later can be realized, and the computer 100 a functions as the system 100 .

[0071] The ROM 110b is composed of a mask programmable read-only memory (MASK ROM), PROM, EPROM, EEPROM, and the like, and stores computer programs executed by the CPU 110a, data for executing these programs, and the like.

[0072] The RAM 110c is composed of SRAM, DRAM, or the like. RAM 110c is used to read computer programs stored in ROM 110b and hard disk 110d. And it is utilized as the execution space of CPU110a at the time of executing these computer programs.

[0073] The hard disk 110d stores various computer programs for the CPU 110a to execute, such as an operating system and application programs, and data for executing the computer programs. An application program ...

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Abstract

The invention provides a simulating system of functions of biological organs, which is used for expressing the biological model of the functions of biological organs through a mathematical model and simulating the functions of biological organs through a computer. The simulating system comprises an input part which receives the measured time-series data input that indicates the biological response of a person to be examined; a reference data generation unit which speculates the biological response of the person to be examined in an unmeasured time in the measured data according to the measured time-series data input and generates the time-series reference data that expresses the biological response of the person to be examined; a virtual biological organ generation unit which generates a virtual biological organ that simulates and reproduces the functions of the biological organ of the person to be examined according to the time-series reference data.

Description

Technical field: [0001] The present invention relates to a computer simulation system for simulating the functions of biological organs, especially the functions of glucose uptake, storage and metabolism, insulin secretion, transport and action in biological organs. Background technique: [0002] The concentration of substances in the living body, especially the concentration of blood sugar and blood insulin, has been recorded using a numerical model for the medical reason that it is representative in the diagnosis of diabetes. The numerical model used here can be, for example, Bergman's minimal model (Bergman's minimalmode1) (such as: Bergman et al., American Journal of Physiology, vol.236 (6), p.E-667-77 (1979), and Bergman et al., Journal of Clinical Investigation, vol. 68(6), p. 1456-67(1981)). [0003] This minimal model takes blood sugar level, plasma insulin concentration, and insulin action amount at the point of action of insulin in peripheral tissues, that is, rem...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06F17/00A61B10/00A61B5/00G06Q50/00A61B5/145G06Q50/10G09B9/00G16H10/60G16Z99/00
CPCG06F19/3437G16H50/50G16Z99/00
Inventor 高地泰浩齐太计雄清家圣嘉
Owner SYSMEX CORP
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