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54 results about "Biological modeling" patented technology

In the sense of a mathematical model, a biological model can be constructed to gain a deeper understanding of an organism, an ecosystem, a genetic lineage, or a wide variety of other topics in biology. Using mathematics, people can set up and test a model.

Digital lake three-dimensional visualized simulation method and simulation platform based on OSG

InactiveCN103559739AThe need for realistic simulationMeet the needs of 3D visualization simulationSpecial data processing applicationsICT adaptationTerrainGeographic site
The invention provides a digital lake three-dimensional visualized simulation method and simulation platform based on an OSG. The digital lake three-dimensional visualized simulation method includes the following steps that a three-dimensional digital terrain model, a ground feature model and an earth surface derivative model of the region where a lake is located are built; the ground feature model and the earth surface derivative model are loaded to the corresponding geographical positions of the three-dimensional digital terrain model to obtain a three-dimensional digital terrain and geographical environment scene; based on the three-dimensional digital terrain and geographical environment scene, an OSD module is used as a bottom layer three-dimensional rendering engine for scene rendering; meanwhile, an OsgOcean module is utilized to further simulate a simulation rendering water current and weather effect to obtain a three-dimensional digital lake terrain environment scene; a water current scene and a weather effect scene obtained through simulation are updated under the control of a man-machine interaction mechanism. The digital lake three-dimensional visualized simulation method and simulation platform have the advantages of being convenient to operate, easy to expand, efficient, and capable of achieving real-time performance and meeting the requirement for wide-range terrain and mass spatial data three-dimensional visualized simulation.
Owner:HUAZHONG UNIV OF SCI & TECH

Biological model of steroids hormone pollutant in foods and feeds established by utilizing Caenorhadits elegans and method thereof

The invention relates to a biological model of steroids hormone pollutant in foods and feeds established by utilizing Caenorhadits elegans and a method thereof, belonging to the field of a safety detection technique of foods and feeds. The biological model of the steroids hormone pollutant in the foods and the feeds is established by utilizing the Caenorhadits elegans. The method of the invention is characterized in that the Caenorhadits elegans is utilized to establish a biological model of steroids hormone pure products; the Caenorhadits elegans is utilized to establish the biological model of steroids hormone in the foods; and the Caenorhadits elegans is utilized to establish a biological model of steroids hormone in the feeds. The invention has the beneficial effects of important significance of the research of the steroids hormone to influence on human health, and short period, high efficiency, conciseness and convenience of the experiment course, less requirements on instruments, low cost and great application value. Moreover, the period of the Caenorhadits elegans from the first stage of larvae to the stage of oviposition and the generation time are detected to identify the precocity phenomenon of organisms under the influence of the steroids hormone by exposing the steroids hormone of the Caenorhadits elegans in the first stage of the larvae.
Owner:CHANGCHUN UNIV OF SCI & TECH

Model method for calculating equivalent uniform dosage of radiotherapy

PendingCN109712714ASolve the problem of large deviation in survival rate predictionAvoid difficultiesMedical simulationHigh cellOriginal data
The invention discloses a model method for calculating an equivalent uniform dosage of radiotherapy, wherein an LQ model is not fundamentally changed and a cell survival condition in a single large dose can be well reflected. Effectiveness of original clinical experience is ensured, and the method can be used for effect evaluation of large dose irradiation after slight correction of the original data. Based on the equivalent uniform dose of a segmented secondary function model, by means of a formula, a treatment planning system can quickly acquire the equivalent uniform doses of a tumor and anormal organization, thereby facilitating comparative evaluation of treatment plans with different dose segmentation modes and different dose distribution patterns. The segmented secondary function model is used for settling a problem of high cell survival rate prediction deviation after performing large-dose irradiation by a traditional linear secondary model. The equivalent uniform dosage modelbased on the model realizes comparison of the treatment effects in different dose distributions. After introducing latent doubling time, the advantages of single large-dose irradiation at an aspect ofovercoming cell proliferation is presented, and a difficulty in clinical application of a radiation biological model is basically solved.
Owner:戴立言 +1

Ancient biological fossil three-dimensional model reconstruction auxiliary device

The invention discloses an ancient biological fossil three-dimensional model reconstruction auxiliary device which comprises a supporting frame, a cross, a supporting module, a connecting module, a telescopic clamping module, a sliding rope, a displacement rod and a modeling module. According to the ancient biological fossil three-dimensional model reconstruction auxiliary device, ancient organism model modeling of any form can be achieved, the stability of a model can be guaranteed in the modeling process, and the situation that the model turns on one side and topples over in the modeling process is avoided. The ancient biological fossil three-dimensional model reconstruction auxiliary device is wide in application range and high in practicability, can be suitable for three-dimensional modeling of various ancient organisms in any form, and can also be suitable for three-dimensional modeling work of any other object. The problem that in the prior art, in the modeling process of large ancient organisms or objects with the upper gravity centers, the situation that due to the fact that the modeling process is performed from bottom to top, a model is prone to side turning and toppling due to the fact that the gravity centers gradually deviate upwards or deviate from the center is solved.
Owner:ANHUI UNIV OF SCI & TECH

Tool for in vitro-in vivo correlation

A biological modeling system and method for enhanced computer-aided analysis of biological response data provides information synthesized from immediate and extended release in vivo data and in vitro data. An executable model of a biological system is developed from information and structures based on the data. In a preferred embodiment, a two stage approach to modeling is used in the development of an IVIVC. The first stage of the procedure is deconvolution, where the percentage of drug absorbed is determined. In the second stage, the in vivo percentage absorbed data is correlated to the in vitro fraction or percentage dissolved data. This correlation then represents a point-to-point relationship between the in vitro dissolution and the in vivo input rate of the drug from the dosage form. In such a correlation, the in vitro dissolution and in vivo absorption profiles are either directly superimposable or may be made to be superimposable by the use of a scaling factor. Prior to the deconvolution stage, a unit impulse response function can be determined from immediate-release concentration-time data. This impulse response function is used in the deconvolution process to determine the in vivo percent absorbed for the extended release formulations. A nonlinear IVIVC model is developed that can incorporate time-scaling and time-shifting into the model if needed. After the two-stage modeling is completed, the predictability of the developed IVIVC model is evaluated by both internal and external validation.
Owner:GLOBOMAX
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