The invention provides a format verification method and system for a nuclear power large-scale comprehensive report. The format verification method comprises the following steps: S1, obtaining and setting a template standard associated with a report to be verified; s2, reading a verification object selected by a user from a report to be verified, carrying out format, content and abbreviation checkon the verification object according to the template standard, and judging whether the verification object has an error problem or not; if yes, prompting the user of the error problem; and S3, positioning an error problem needing to be modified according to the selection of the user, and manually or automatically modifying the positioned error problem. The format checking system comprises a setting module, a document checking module and a modifying module. According to the format verification method and system provided by the invention, automatic operation of format verification is realized,the processing efficiency is improved, and meanwhile, the report document quality is effectively ensured.