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30results about How to "Laborious and time-consuming" patented technology

Method of producing textile emblems with pressure sensitive adhesive properties

A new device, pressure sensitive adhesive system for bonding textiles and a method for producing integrated textile emblems such as patches, emblems, emblems, labels and cut textile parts including wovens, knits and nonwoven structures made of both natural and or synthetic fibers incorporating a pressure sensitive adhesive. The resulting room temperature pressure sensitive-patch eliminates tedious and cost intensive sewing operations (embroidery) and or heat-sealing operations (heat transfers) to other textile products such as apparel and or accessories, headwear, crafts home furnishings and luggage. The room temperature pressure sensitive adhesive-patches comprise at least: 1) a top base layer which can be a knitted, woven or non-woven fabric sheet that is stitched, printed, embossed, etched, engraved, flocked or dyed to form a decorative element, and which may be cut into a desired shape; 2) a pressure-sensitive adhesive layer adhered to the top base layer that comprises an adhesive having good medium-to-high surface energy properties, is not water soluble and is of adequate thickness to provide a sustainable bond capable of surviving multiple washes to textile-based products such as apparel and or accessories, headwear, crafts home furnishings and luggage. The room temperature pressure sensitive-patches may be transferred by simple pressure, thereby eliminating the burden and expense of thermal or mechanical (stitched) bonding.
Owner:BAQAI NAVAID +2

Tool for in vitro-in vivo correlation

A biological modeling system and method for enhanced computer-aided analysis of biological response data provides information synthesized from immediate and extended release in vivo data and in vitro data. An executable model of a biological system is developed from information and structures based on the data. In a preferred embodiment, a two stage approach to modeling is used in the development of an IVIVC. The first stage of the procedure is deconvolution, where the percentage of drug absorbed is determined. In the second stage, the in vivo percentage absorbed data is correlated to the in vitro fraction or percentage dissolved data. This correlation then represents a point-to-point relationship between the in vitro dissolution and the in vivo input rate of the drug from the dosage form. In such a correlation, the in vitro dissolution and in vivo absorption profiles are either directly superimposable or may be made to be superimposable by the use of a scaling factor. Prior to the deconvolution stage, a unit impulse response function can be determined from immediate-release concentration-time data. This impulse response function is used in the deconvolution process to determine the in vivo percent absorbed for the extended release formulations. A nonlinear IVIVC model is developed that can incorporate time-scaling and time-shifting into the model if needed. After the two-stage modeling is completed, the predictability of the developed IVIVC model is evaluated by both internal and external validation.
Owner:GLOBOMAX
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