Apparatus and method for determining an injection point for targeted drug delivery
An injection point and equipment technology, which is applied in the fields of instruments, applications, and medical sciences for radiological diagnosis, can solve the problem of not being used to determine the injection point, etc., and achieve the effect of improving ease of use and reducing consumption.
Active Publication Date: 2012-09-26
KONINK PHILIPS ELECTRONICS NV
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Problems solved by technology
Blood flow measurements were made by infusion, but flow characteristics were not used to determine the infusion point
Method used
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Embodiment Construction
[0033] figure 1 Schematically shows a block diagram of a device according to the invention for the X-ray-supported evaluation of possible locations of targeted drug administration. Before the optimal injection point for injecting the drug into or into the body 1 can be determined, image data of the patient 1 needs to be acquired by a data acquisition device 2, such as an X-ray for 3D rotational angiography (3DRA). Optical equipment or medical diagnostic imaging devices such as CT, MR or ultrasound equipment. The obtained image data is usually stored in the memory 3 . The subsequent processing by the data processing device 4 can of course take place immediately after data acquisition or data storage, but also at any time thereafter.
[0034] In order to assess the effect of chemoembolization, the distribution of the contrast agent in the vascular tree is analyzed during the acquisition of dynamic data showing the delivery of the contrast agent in the vascular tree. For this ...
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The present invention relates to an apparatus for determining an injection point for targeted drug delivery into a patient's body by injection of the drug into a vessel feeding a target area including a target. To provide the interventionalist with an objective and quantitative assessment of potential drug injection points instead of letting him rely on his subjective impression from the visual inspection of DSA sequences, an apparatus is proposed comprising: identification means (41) for identification of a vessel tree topology of vessels feeding said target area, flow determination means (42) for determining the percentage of drug material delivered to said target after injection into different potential injection points in said vessel tree, selection means (43) for selecting as optimalinjection point the potential injection point resulting in the highest percentage of drug delivery to said target.
Description
technical field [0001] The present invention relates to a device and a corresponding method for determining an injection point for targeted drug delivery to a patient's body by injecting the drug into a blood vessel supplying blood to a target area including the target. The invention also relates to a computer program for implementing such a method on a computer. Background technique [0002] Chemoembolization is an effective method for treating unresectable tumors in a minimally invasive manner. Guided by X-rays, the tip of the catheter is threaded into the artery that supplies blood to the tumor. Chemotherapy materials are then injected into the tumor through the catheter. This delivers the chemotherapy directly into the tumor and blocks blood flow to the tumor. [0003] To determine the location of the tumor's main feeding artery, a contrast agent is injected into the candidate vessel and a series of DSA (digital subtraction angiography) images are acquired. After a v...
Claims
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IPC IPC(8): G06T7/00G06T5/00A61B6/00A61B5/0275
CPCA61B5/4839A61B6/481G06T7/004G06T2207/20012A61B6/507A61M2005/14292A61B6/504G06T7/0012A61B5/489G06T2207/30101G06T7/70
Inventor A·格罗思J·维塞J·布雷德诺
Owner KONINK PHILIPS ELECTRONICS NV