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Traditional Chinese medicine composition, preparation method and use of the same

The technology of a composition and traditional Chinese medicine is applied in the field of preparation of the traditional Chinese medicine composition, which can solve the problems of poor patient tolerance, large negative effects and the like, and achieve the effects of less irritation, high bioavailability and fast disintegration

Inactive Publication Date: 2008-02-27
杨文龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used therapeutic drugs include ion antagonists, cerebral circulation promoters and cholinesterase inhibitors. Although they have certain curative effects, they have relatively large negative effects and are poorly tolerated by patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] Prescription: musk 0.7g, Chuanxiong 80g, safflower 100g, earthworm 110g, salvia miltiorrhiza 160g, curcuma 100g, peach kernel 120g, trigonum 100g.

[0102] Preparation method: decoct Chuanxiong, Danshen, Zedoary, peach kernel, and Sanleng with water twice, the first time for 2 hours, and the second time for 1.5 hours, combine the decoctions, and concentrate to an extract with a relative density of 1.20 (60°C); Wherein the amount of water added is respectively 8 and 10 times of the total weight of Chuanxiong, Danshen, Curcuma, peach kernel and trigonum;

[0103] Crush safflower and earthworm into fine powder, add musk to grind, and mix with the above-mentioned extract evenly to obtain the traditional Chinese medicine composition.

[0104] Mix the traditional Chinese medicine composition and starch evenly, dry, granulate, vacuum-dry the granules at a temperature of 65°C until the moisture content is 3%, add 0.3% (w / w) magnesium stearate, press into tablets, and film-coat....

Embodiment 2

[0107] Prescription: musk 0.9g, Chuanxiong 35g, safflower 80g, earthworm 100g, salvia miltiorrhiza 200g, curcuma 80g, peach kernel 100g, trigonum 120g.

[0108] Preparation method: decoct Chuanxiong, danshen, zedoary, peach kernels, and triangular ribs with water for 3 times, the first time for 2 hours, the second time for 3 hours, and the third time for 1 hour, combine the decoctions, concentrate to a relative density of 1.10 (60 ℃) extract; wherein the amount of water added is respectively 6, 8, and 10 times the total weight of Chuanxiong, Danshen, Curcuma, peach kernel, and trigonum;

[0109] Crush safflower and earthworm into fine powder, add musk to grind, and mix with the above-mentioned extract evenly to obtain the traditional Chinese medicine composition.

[0110] Mix the traditional Chinese medicine composition and starch evenly, dry, granulate, vacuum-dry the granules at a temperature of 60°C until the moisture content is 5%, add 0.1% (w / w) magnesium stearate, press ...

Embodiment 3

[0113] Prescription: musk 0.4g, Chuanxiong 100g, safflower 70g, earthworm 90g, salvia miltiorrhiza 100g, curcuma 140g, peach kernel 140g, trigonum 80g.

[0114] Preparation method: decoct Chuanxiong, Danshen, Zedoary, peach kernel, and Sanleng with water twice, the first time for 2 hours, and the second time for 3 hours, combine the decoctions, and concentrate to an extract with a relative density of 1.30 (60°C); The amount of water added is 10, 6, and 8 times the total weight of Chuanxiong, Danshen, Curcuma, peach kernel, and trigonum respectively;

[0115] Crush safflower and earthworm into fine powder, add musk to grind, and mix with the above-mentioned extract evenly to obtain the traditional Chinese medicine composition.

[0116] Mix the traditional Chinese medicine composition and starch evenly, dry, granulate, vacuum-dry the granules at a temperature of 70°C until the water content is 0.5%, add 0.5% (w / w) magnesium stearate, press into tablets, and film-coat. Instantly...

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PUM

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Abstract

The invention discloses a Chinese medicinal composition, its preparing process and use, wherein the preparing process consists of watering and grilling Ligusticum wallichii, root of red rooted saliva, zedoary, peach kernels and common burreed tuber three times (1-3 hours each time), merging the grilling liquids, concentrating into concrete with specific gravity of 1. 10-1. 30 (60 deg C. ), disintegrating safflower and earthworm into fine powders, charging musk and pharmaceutically acceptable medicinal auxiliary materials, and mixing with the concrete homogeneously. The composition can be used for treating cerebral embolism, arteriosclerosis, coronary disease, senile dementia, light-headedness, hemiparalysis, brain trauma and cerebral hemorrhage sequelae.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating cerebral embolism, arteriosclerosis, coronary heart disease, senile dementia, dizziness, hemiplegia, traumatic brain injury and sequelae of cerebral hemorrhage. It relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] With the aging of our country's population becoming more and more serious, senile dementia has become a serious social problem. According to statistics, the prevalence of senile dementia accounts for about 10% of the population aged 60, among which Alzheimer's dementia and vascular dementia are the most common. Vascular dementia is a mental retardation syndrome caused by cerebrovascular disease. Due to vascular disease in the brain, or lesions in the blood vessels outside the brain and the heart indirectly affect the blood vessels in the brai...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/16A61K9/20A61K9/28A61K9/48A61P9/10A61P7/02A61P25/28A61P25/00A61K35/64A61K35/55A61K35/62
Inventor 杨文龙
Owner 杨文龙
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