Applications of ash tree flowers polysaccharide for preparing preventing and controlling pig virosis medicament

A technology for Grifola frondosa polysaccharide and viral diseases, which is applied in directions such as drug combinations, pharmaceutical formulations, organic active ingredients, etc., to achieve the effects of low treatment cost, good treatment effect, and no toxic and side effects

Active Publication Date: 2008-08-27
TIANJIN SHENGJI GRP CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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However, there are no reports on the clinical research and product development of Grif

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  • Applications of ash tree flowers polysaccharide for preparing preventing and controlling pig virosis medicament
  • Applications of ash tree flowers polysaccharide for preparing preventing and controlling pig virosis medicament

Examples

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Example Embodiment

[0012] Example 1

[0013] Study on Grifola frondosa polysaccharide in the treatment of porcine rotavirus enteritis

[0014] Materials and methods

[0015] Test animals, grouping and test methods

[0016] According to clinical observations and laboratory diagnosis, the following 40 piglets were selected as confirmed rotavirus enteritis and divided into treatment group and control group. The age, clinical manifestation, and severity of the disease of the two groups were the same.

[0017] In the treatment group, there were 20 cases in each control group, and the treatment group was intramuscularly injected with Grifola frondosa polysaccharide at 5.0 mg / Kg, 0.5 ml / kg each time, twice a day. The control group was given Smecta orally, 0.01~0.15g / kg each time, twice a day. After administration, observe the mental state, body temperature, shape and color of feces and the suckling or feeding status of the piglets every day.

[0018] Efficacy determination

[0019] The clinical symptoms of...

Example Embodiment

[0025] Example 2

[0026] Experimental study of Grifola frondosa polysaccharide in preventing and treating swine epidemic diarrhea

[0027] 1 Test animals, grouping and test methods

[0028] 1.1 Feeding and management of test pigs All tested piglets are raised with their sows in farrowing houses under the same conditions or raised on a cement floor, and routinely disinfected once a week.

[0029] 1.2 Treatment test According to clinical observations and laboratory tests, the following 45 pigs from 1 to 25 days old that have been diagnosed with porcine epidemic diarrhea were selected, and the piglets of different ages were classified according to the time of onset, symptoms, litters, weight, and sex. Divide into three groups A, B, and C randomly. Piglets in group A were injected intramuscularly with Grifola frondosa polysaccharide at 8.0 mg / Kg; piglets in groups B and C were injected intramuscularly with physiological saline and astragalus polysaccharide at the recommended dose of ...

Example Embodiment

[0036] Example 3

[0037] Examples of Grifola frondosa polysaccharides in the treatment of swine transmissible gastroenteritis

[0038] On March 5, 2008, piglets in a breeding farm in Tianjin showed the same symptoms one after another: diarrhea, fever, lack of energy, and anorexia. After March 8, it was found that the mortality rate of pigs increased, and the feed intake decreased rapidly. Every 100 pigs per day There were 1 to 2 deaths, and the most serious death was about 6 deaths per day.

[0039] In view of the above phenomenon, it is recommended to use Grifola frondosa polysaccharide intramuscular injection at 100mg / pig for 3 to 5 days. In addition, with multi-dimensional electrolytes, death can be quickly controlled, the pigs will recover their mental state, and the rate of invention and mortality will be significantly reduced.

[0040] Analysis: Diagnosis by necropsy and pathology: Porcine transmissible gastroenteritis.

[0041] Summary: Similar symptoms, early detection an...

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Abstract

The invention relates to the use of polysaccharides of Grifola frondosa in preparing drugs for controlling viral diseases in pigs, particularly to the use for controlling porcine rotavirus enteritis, porcine epidemic diarrhea and porcine transmissible gastroenteritis. For use, polysaccharides of Grifola frondosa are injected intramuscularly at a dose of 1.0-50 mg/kg, twice daily or mixed uniformly with a premix feed at a weight percentage of 0.1-10%. The premix feed is commercially available and pigs are fed ad libitum. The invention has the advantages that: the invention provide a new natural medicine for controlling viral diseases in pigs and improving porcine immunity in clinic; the natural medicine has high safety, definite effectiveness and controllable quality; and the natural medicine has easily-accessible raw materials, no toxicity and side effect and no risk of inducing drug resistance.

Description

technical field [0001] The invention relates to the application of the frondosa frondosa polysaccharide, in particular to the application of the frondosa frondosa polysaccharide in the preparation of medicines for preventing and treating viral diseases of pigs. Background technique [0002] Among pig diseases, virus infection is the most costly to the pig farming industry. In large-scale pig production, due to the influence of many factors, the incidence of viral diseases such as porcine parvovirus, swine fever virus, and porcine blue ear virus is as high as 5-50%, and the fatality rate is as high as 1%-10%. Pig production causes great economic losses. For example, among the various causes of porcine diarrhea, the harm of viral diarrhea is the most serious, which can cause the death of piglets, fat loss of adult pigs, reduction of feed remuneration, increase of labor costs and medical expenses. Porcine transmissible gastroenteritis, porcine epidemic diarrhea, and porcine r...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61P1/04A61P1/12
Inventor 古长庆
Owner TIANJIN SHENGJI GRP CO LTD
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