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Bursa of fabricius vaccine oral liquid synergistic agent for poultry and preparation method thereof

A technology of oral liquid and bursa, which is applied in the field of poultry pharmaceutical composition and its preparation, can solve the problems of limited and uncertain immune efficacy of vaccines, achieve the effects of no toxic side effects, improve cellular immune function, and enhance immune effect

Inactive Publication Date: 2008-12-03
雷清莲 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Types of Vaccines Currently used vaccines mainly include inactivated vaccines, live vaccines and combined vaccines (inactivated vaccines or live vaccines). Confirmed, bringing great uncertainty to the prevention and treatment of bursal disease

Method used

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  • Bursa of fabricius vaccine oral liquid synergistic agent for poultry and preparation method thereof
  • Bursa of fabricius vaccine oral liquid synergistic agent for poultry and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1: Preparation of Oral Liquid Synergist 1 of the present invention

[0020] (1) Weigh 10 grams of Burnet, 10 grams of Rhizoma Chuanxiong, 5 grams of Lily, 10 grams of Gardenia, 15 grams of Qinpi, 5 grams of Sijiqing, 15 grams of Helicoptera, 2 grams of Snake Gallbladder, 10 grams of Ox Gallbladder, and 40 grams of Aloe Vera , rock sugar 25 grams.

[0021] (2) Add water to the raw material and decoct twice. It is advisable to add water each time to cover the raw material surface. Combine the two decoctions, filter to obtain the filtrate, concentrate it into an extract with a specific gravity of 1.35, and add 85-95% edible glacial acetic acid Carry out leaching, recover glacial acetic acid and concentrate, and dry at 45-50°C to obtain 14.23 grams of dry extract;

[0022] (3) Crush the dry extract into powder, then add 1000ml of 85-95% edible glacial acetic acid, and stir well.

Embodiment 2

[0023] Embodiment two: preparation of oral liquid synergist 2 of the present invention

[0024] (1) Weigh 20 grams of Burnet, 25 grams of Rhizoma Chuanxiong, 20 grams of Lily, 20 grams of Gardenia, 20 grams of Qinpi, 20 grams of Sijiqing, 30 grams of Sheltrum, 5 grams of Snake Gallbladder, 20 grams of Ox Gallbladder, and 60 grams of Aloe Vera , 40 grams of rock sugar.

[0025] (2) Add water to the raw material and decoct twice. It is advisable to add water each time to cover the raw material surface. Combine the two decoctions, filter to obtain the filtrate, concentrate it into an extract with a specific gravity of 1.35, and add 85-95% edible glacial acetic acid Carry out leaching, recover glacial acetic acid and concentrate, and dry at 45-50°C to obtain 25.2 grams of dry extract;

[0026] (3) Crush the dry extract into powder, then add 2500ml of 85-95% edible glacial acetic acid, and stir well.

Embodiment 3

[0027] Embodiment three: preparation of oral liquid synergist 3 of the present invention

[0028] (1) Weigh 12 grams of Burnet, 12 grams of Rhizoma Chuanxiong, 8 grams of Lily, 12 grams of Gardenia, 18 grams of Qinpi, 16 grams of Sijiqing, 16 grams of Helicoptera, 3 grams of Snake Gallbladder, 13 grams of Ox Gallbladder, and 35 grams of Aloe Vera , Rock sugar 35 grams.

[0029] (2) Add water to the raw material and decoct twice. It is advisable to add water each time to cover the raw material surface. Combine the two decoctions, filter to obtain the filtrate, concentrate it into an extract with a specific gravity of 1.35, and add 85-95% edible glacial acetic acid Carry out leaching, recover glacial acetic acid and concentrate, and dry at 45-50°C to obtain 17.2 grams of dry extract;

[0030] (3) Crush the dry extract into powder, then add 2000ml of 85-95% edible glacial acetic acid, and stir well.

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Abstract

The invention relates to a poultry medicine composition and a preparation method thereof. A bursa fabricius vaccine oral liquid synergistic agent is mainly prepared by the following raw materials by weight portion: 10 to 20 portions of sanguisorba, 10 to 25 portions of Chuanxiong rhizome, 5 to 20 portions of lily, 10 t0 20 portions of gardenia, 15 to 20 portions of ash bark, 5 to 20 portions of folium ilicis chinensis, 15 to 30 portions of carpet bugle, 2 to 5 portions of snake gall, 10 to 20 portions of ox-gall, 40 to 60 portions of Chinese aloe and 25 to 40 portions of crystal sugar. The oral liquid synergistic agent can improve the immunologic function of cells of poultry organisms, resist to stress, strengthen antibodies, improve the immunity by 3 to 6 times, eliminate mutual interference between vaccines, and strengthen the immune effect of combined vaccines; and the product has an uncontemplated effect of treating both manifestation and root cause of diseases. Moreover, the oral liquid synergistic agent has the advantages of convenience in drinking and administration, high absorptivity, wide distribution, no medicine residue, no toxic side effect, and wide safe range.

Description

【Technical field】 [0001] The invention relates to a pharmaceutical composition for poultry and a preparation method thereof. 【Background technique】 [0002] Chicken infectious bursal disease, also known as supracavitary bursitis and infectious bursal disease, is an acute and highly contagious infectious disease of chicks caused by infectious bursal disease virus in the family Reoviridae. Chicken Bursa. It is characterized by diarrhea, exhaustion, significant inflammation and enlargement of the bursa of Fabricius first, followed by atrophy, and finally the death of affected chickens. The disease occurs in major chicken-raising countries in the world. China first isolated the virus in Beijing in 1980, and then found the disease in Shanghai, Guangzhou, Harbin, Nanjing and other places. [0003] The disease only occurs in chickens and is highly contagious. Chickens aged 2 to 6 weeks are most susceptible. Therefore, maternal antibodies are disappearing at this time, and the dev...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/10A61P31/14A61P37/04A61K35/58A61K35/413A61K35/583
Inventor 谢兴荣刘治西唐兆新郭世宁汪连涛王芝武帮勇吴国辉陈胜叶亚多潘永发林仕
Owner 雷清莲
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