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Chinese medicinal composition for treating coronary disease, stenocardia

A composition, angina pectoris technology, applied in the directions of drug combination, drug delivery, cardiovascular system diseases, etc., can solve problems such as treatment market gaps, and achieve the effects of increasing coronary blood flow, reducing myocardial oxygen consumption, and dilating coronary blood vessels

Active Publication Date: 2010-11-03
BEIJING TONGRENTANG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, Chinese patent medicines also have the effects of nourishing qi and nourishing yin, promoting qi and blood circulation, calming the heart and relieving pain. For those who have the functions of nourishing yin, promoting qi and promoting blood circulation, the treatment market is still relatively blank, so the market is in urgent need of developing a traditional Chinese medicine for the treatment of coronary heart disease and angina pectoris with definite and significant curative effect, sophisticated technology and stable drug quality. Significant development significance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] prescription:

[0102] Chuanxiong 140g Ginseng 150g Alisma 90g Sandalwood 100g

[0103] Ophiopogon japonicus 110g Danshen 160g Schisandra 40g Pueraria 90g

[0104] Borneol 3g Panax notoginseng 110g

[0105] Preparation method: the above ten flavors: Soak sandalwood water for 1 hour, extract volatile oil, extract volatile oil with β-cyclodextrin inclusion, dry at 50 ℃ for later use, extract the residue with salvia miltiorrhiza twice, each time for two hours. Concentrate the extract to a relative density of 1.15 (50°C), add ethanol to make the alcohol content reach 60%, and precipitate with alcohol for 24 hours; take the supernatant for later use. The rest of Chuanxiong, ginseng, Alisma, sandalwood, Ophiopogon japonicus, Salvia miltiorrhiza, Schisandra chinensis, Pueraria lobata, and Panax notoginseng were refluxed twice with 70% ethanol for 2 hours each time, filtered, combined filtrates, combined with salvia miltiorrhiza alcohol precipitation, and recovered Ethanol, ...

Embodiment 2

[0107] prescription:

[0108] Chuanxiong 150g Ginseng 333g Alisma 130g Sandalwood 150g

[0109] Ophiopogon japonicus 180g Danshen 165g Schisandra 130g Pueraria 135g

[0110] Borneol 2g Panax notoginseng 66g

[0111] Preparation method: the preparation of the composition is the same as in Example 1.

[0112]Granules: Prepare granules according to the routine to obtain the granules of the present invention.

[0113] The result shows: the composition granule of the present invention meets relevant regulations under the granule item.

Embodiment 3

[0115] prescription:

[0116] Chuanxiong 135g Ginseng 333g Alisma 56g Sandalwood 333g

[0117] Ophiopogon japonicus 333g Danshen 666g Schisandra 36g Pueraria 56g

[0118] Borneol 33g Panax notoginseng 33g

[0119] Preparation method: the preparation of the composition is the same as in Example 1.

[0120] Tablet: After mixing the extracts of the above-mentioned composition of the present invention, add binders such as dextrin, mix thoroughly, place at 60-80°C for vacuum drying, pulverize, add fillers such as starch, lubricants such as magnesium stearate, and Disintegrants such as sodium carboxymethylcellulose are mixed evenly, granulated, and compressed into tablets to obtain the tablet of the present invention.

[0121] The result shows: the composition tablet of the present invention meets relevant regulations under the tablet item.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition, a medicine containing the composition, a preparation method for the medicine and an application of the medicine, wherein, the compositions by weight portion of the composition are 0.4 to 4 portions of Chuanxiong rhizome, 0.6 to 6 portions of ginseng, 0.1 to 3 portions of alisma orientale, 0.5 to 5 portions of sandalwood, 0.5 to 3 portions of dwarf lilyturf root, 0.5 to 5 portions of Salvia miltiorrhiza, 0.1 to 3 portions of shizandra, 0.1 to 3 portions of kudzu, 0.1 to 1 portion of pseudo-ginseng and 0.001 to 0.1 portion of borneol; and the compositions can come from traditional Chinese medicines or traditional Chinese medicine water extract equivalent to the crude medicine amount of the traditional Chinese medicines. The traditional Chinese medicine composition can be used for treating diseases such as coronary heart disease, angina pectoris and so on.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, specifically, a traditional Chinese medicine composition for treating coronary heart disease and angina pectoris. Chinese herbal extracts. Background technique [0002] Coronary atherosclerotic heart disease is referred to as coronary heart disease, also known as ischemic heart disease, including coronary atherosclerosis that narrows or blocks it, or changes in its function—myocardial ischemic disease caused by spasm, angina pectoris is A common type of disease. Angina pectoris is a clinical symptom caused by atherosclerotic coronary artery insufficiency and acute myocardial ischemia and hypoxia. [0003] Coronary heart disease mostly occurs in people over 40 years old, and its morbidity and fatality rate increase with age. Men are higher than women, and the average age of onset in women is 10 years later than men. However, the prevalence of coronary heart disease in postmenopausal ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K9/00A61K9/06A61K9/14A61K9/16A61K9/20A61K9/48A61K47/40A61P9/10A61K31/045
Inventor 张绍来季绍良李志猛张维钧彭鹏张蔚张学著
Owner BEIJING TONGRENTANG CO LTD
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