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Chinese medicinal composition with function for reducing blood pressure and preparation method thereof

A composition and technology for lowering blood pressure, applied in the direction of drug combination, medical preparations containing active ingredients, food preparation, etc., can solve the problems of side effects and can not cure the root cause, and achieve the reduction of plasma renin activity and angiotensin II level, reduce The effect of myocardial oxygen consumption and hemodynamic improvement

Inactive Publication Date: 2009-05-20
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, western medicine often uses western medicines such as sympathetic nerve inhibitors, nerve blockers, vasodilators, and central blood pressure medicines to treat hypertension, but these medicines have certain side effects and cannot cure the root cause

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The preparation of the capsule of Chinese medicine composition of the present invention

[0032] a) Weighing 7kg perilla leaves, 9kg apocynum leaves, 6kg gastrodia elata, and 9kg uncaria, after screening, washing, drying, pulverizing for subsequent use;

[0033] b) extracting volatile oil from perilla leaves by steam distillation, and preparing cyclodextrin inclusion compound by inclusion of volatile oil with cyclodextrin;

[0034] c) Perilla leaf dregs, Apocynum leaves, Gastrodia elata plus 70% ethanol to extract once, add Uncaria, then extract once with 70% ethanol, combine the two filtrates, recover ethanol, concentrate under reduced pressure to a relative density of 60 Measure 1.25-1.30 at ℃, dry under reduced pressure to obtain dry extract;

[0035] d) Crush the dry extract into powder, add cyclodextrin inclusion complex, and pack into hard gelatin capsules.

Embodiment 2

[0037] The preparation of the granule of Chinese medicine composition of the present invention

[0038] a) Take by weighing 5kg perilla leaves, 6kg apocynum leaves, 3kg gastrodia elata, and 3kg uncaria, which are screened, washed, dried, and pulverized for subsequent use;

[0039] b) extracting volatile oil from perilla leaves by steam distillation, and preparing cyclodextrin inclusion compound by inclusion of volatile oil with cyclodextrin;

[0040] c) Perilla leaf dregs, Apocynum leaves, Gastrodia elata plus 70% ethanol to extract once, add Uncaria, then extract once with 70% ethanol, combine the two filtrates, recover ethanol, concentrate under reduced pressure to a relative density of 60 Measure 1.25-1.30 at ℃, dry under reduced pressure to obtain dry extract;

[0041] d) Grinding the dry extract into powder, adding cyclodextrin inclusion compound, adding ethanol as a binder, and adding an appropriate amount of starch as a filler to make granules.

Embodiment 3

[0043] The preparation of the granule of Chinese medicine composition of the present invention

[0044] a) Take by weighing 9kg perilla leaves, 12kg apocynum leaves, 9kg gastrodia elata, and 12kg uncaria, which are screened, washed, dried, and pulverized for subsequent use;

[0045] b) extracting volatile oil from perilla leaves by steam distillation, and preparing cyclodextrin inclusion compound by inclusion of volatile oil with cyclodextrin;

[0046] c) Perilla leaf medicinal residues, Apocynum leaves, Gastrodia elata were extracted once with water, added Uncaria, then extracted once with water, the filtrates were combined twice, ethanol was recovered, concentrated under reduced pressure to a relative density of 60°C and measured at 1.25-1.30, Drying under reduced pressure to obtain dry extract;

[0047] d) Grinding the dry extract into powder, adding cyclodextrin inclusion compound, adding ethanol as a binder, and adding an appropriate amount of starch as a filler to make ...

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Abstract

The invention discloses a traditional Chinese medicine composition with the function of reducing blood pressure, as well as a preparation method thereof. The traditional Chinese medicine composition is prepared from perilla leaves, Apocynum venetum, rhizoma gastrodiae and uncaria according to a certain weight mixture ratio, and can be prepared to be any common orally taken medicament. The traditional Chinese medicine composition has the efficacy of reducing blood pressure and can be used for treating hypertension.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition with the function of lowering blood pressure and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Hypertension is a common disease, the cause of which is increased blood lipids, narrowed blood vessel walls, or decreased hemolyzed substances in the blood, thrombosis, resulting in blocked blood flow, or overeating fat, eating salt, causing excessive subcutaneous fat, compressing blood vessels, Caused by excess blood flow. [0003] At present, Western medicine such as sympathetic nerve inhibitors, nerve blockers, vasodilators, and central hypotensive drugs are often used in the treatment of hypertension by Western medicine, but these drugs have certain side effects and cannot cure the root cause. Contents of the invention [0004] The object of the present invention is to provide a traditional Chinese medicine composit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P9/12A23L1/30
Inventor 张永丽
Owner BEIJING INCREASEPHARM CORP LTD
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