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Traditional Chinese medicine composition capable of preventing and treating osteoporosis and preparation method thereof

A technology of osteoporosis and composition, applied in the field of medicine, can solve problems such as side effects, complex ingredients of medicines, and the need to further improve the efficacy of medicines

Inactive Publication Date: 2009-06-17
谢林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its pharmaceutical ingredients are relatively complex, have certain side effects, and the efficacy needs to be further improved

Method used

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  • Traditional Chinese medicine composition capable of preventing and treating osteoporosis and preparation method thereof
  • Traditional Chinese medicine composition capable of preventing and treating osteoporosis and preparation method thereof
  • Traditional Chinese medicine composition capable of preventing and treating osteoporosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The effect of the Chinese medicinal composition prepared according to the technical scheme of the present invention on promoting bone formation in an ovariectomized rat model of osteoporosis

[0028] This experiment intends to establish a model of postmenopausal osteoporosis in rats, with the help of modern histopathological examination, dual-energy X-ray bone density analyzer, biochemistry, molecular biology and other methods and methods to systematically observe the effects of traditional Chinese medicine composition on postmenopausal The path of action and mechanism of osteoporosis, preliminary exploration of the mechanism of the drug in preventing and treating postmenopausal osteoporosis (such as promoting bone formation, etc.), to provide scientific and reasonable experimental basis for clinical prevention and treatment of postmenopausal osteoporosis.

[0029] 1. Main experimental materials

[0030] 1.1 Experimental animals:

[0031] Clean SD rat, female, 3 months old,...

Embodiment 2

[0146] The selection of raw medicinal materials is the same as in Example 1, and the preparation steps according to the preferred raw medicinal material ratio are as follows:

[0147] (1) Weigh the raw medicinal materials in the proportions of 29% of Rhizoma Drynariae, 25% of Epimedium, 19% of Achyranthes Bidentata, 20% of Eucommia and 7% of Lujiao Tablets, and set aside;

[0148] (2) The said weight ratio of Achyranthes bidentata was refluxed and extracted twice with 70% ethanol for 1 hour each time, and filtered to obtain the filtrate I and the medicine residue for use;

[0149] (3) Combine the drynaria fortunei, epimedium, eucommia and deer horn tablets with the said weight ratio and step (2) adding water to decocting the Chinese medicine residue twice, the first time adding 9 times the amount of water, the second adding water amount It is 7 times the amount, decocted for 1 hour each time, filtered to obtain filtrate II, and set aside

[0150] (4) Combine the filtrate I and the...

Embodiment 3

[0154] The selection of the original medicinal materials is the same as in Example 1, and the preparation steps according to the optional raw medicinal material ratio are as follows:

[0155] (1) Weigh the raw medicinal materials in proportions of 37% of Rhizoma Drynariae, 30% of Epimedium, 13% of Achyranthes Bidentata, 12% of Eucommia and 8% of Antler Tablets for each serving;

[0156] (2) The said weight ratio of Achyranthes bidentata was refluxed and extracted twice with 70% ethanol for 2.5 hours each time, and filtered to obtain filtrate I and medicine residue for use;

[0157] (3) Decoction of drynaria fortunei, epimedium, eucommia and deer horn tablets in the said weight ratio and step (2) Chinese medicine dregs in water twice, the first time adding 11 times the amount of water, the second time adding water amount It is 9 times the amount, decocted for 2.4 hours each time, filtered to obtain filtrate II for use;

[0158] (4) Combine the filtrate I and the filtrate II, and co...

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Abstract

The invention relates to a medicament which is a Chinese traditional medicine composition preventing and treating osteoporosis, also to a preparation method thereof, belonging to the technical field of medicament. The medicament is mainly made from 25-40% of rhizoma drynariae, 20-35% of barrenwort, 10-25% of radix achyranthis bidentatae, 10-25% of eucommia and 5-15% of antler sheets. The preparation processes are weighing rhizoma drynariae, barrenwort, radix achyranthis bidentatae, eucommia and antler sheets, sequentially extracting radix achyranthis bidentatae with alcohol and filtering to obtain filtrate I and dregs, decocting dregs, rhizoma drynariae, barrenwort and antler sheets with water, filtering to obtain filtrate II, combining the filtrate I and II, and concentrating to make into liquid medicine containing active components. The Chinese traditional medicine formulation provided by the invention has low side effect and relatively good effect on preventing and treating primary osteoporosis.

Description

Technical field [0001] The invention relates to a medicine, which is a traditional Chinese medicine composition for preventing and treating osteoporosis. The invention also relates to a preparation method of the traditional Chinese medicine composition, which belongs to the technical field of medicine. Background technique [0002] Osteoporosis (OP) is a systemic multi-causal skeletal disease that is prone to fractures due to changes in the fine structure of the bones and bone tissues of the whole body, resulting in weakened bone strength and increased bone fragility. "Fall", "gubi", "back pain", "bone dryness", "bone extreme", "fracture", "pre- and post-menopausal symptoms", "deficiency" and other categories. Studies have shown that approximately 75 million people in the United States, Europe, and Japan suffer from osteoporosis to varying degrees. There are also tens of millions of patients in my country, especially in postmenopausal women. The incidence is higher, so modern Chi...

Claims

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Application Information

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IPC IPC(8): A61K36/46A61P19/10A61K35/32
Inventor 谢林
Owner 谢林
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