Anti-rabies virus monoclonal antibody and preparation method and application

A technology of rabies virus and monoclonal antibody, applied in the field of biomedicine, can solve the problems of cumbersome operation of detection methods and the like
CN101560255AInactive Publication Date: 2009-10-21NANJING MEDICAL UNIV +1
0 Cites 28 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
NANJING MEDICAL UNIV
Publication Date
2009-10-21
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses an anti-rabies virus monoclonal antibody and a preparation method and an application, belonging to the field of biomedicine and particularly relating to the preparation of a monoclonal antibody capable of identifying rabies virus and the application. The monoclonal antibody of the invention is screened by indirect Enzyme-linked immunosorbent assay (ELISA), and specificity and affinity thereof combined with antigen are identified by methods such as polyacrylamide gel electrophoresis analysis, speckle ELISA, immunoblot analysis and the like. The anti-rabies virus monoclonal antibody of the invention can be applied in multiple testing methods of antigen of rabies virus and can be also applied in the preparation of rabies virus detecting kit. The anti-rabies virus monoclonal antibody is secreted by anti-rabies virus monoclonal antibody hybridoma cell strain 2C5 with the preservation number being CGMCC No.3014.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The anti-rabies virus monoclonal antibody and its preparation method and application of the present invention relate to the field of biomedicine, in particular to the preparation and application of a monoclonal antibody capable of recognizing rabies virus. Background technique

[0002] Rabies is a worldwide zoonotic disease caused by Rabies virus. Mortality rate is as high as 100% in humans and animals. About 55,000 people die from rabies every year in the world, mainly in developing countries in Asia, Africa and Latin America. Human patients are mostly infected by the bites of sick animals, and have central nervous system infection diseases mainly characterized by hydrophobia, photophobia, dysphagia, and mania. The disease is widespread and has many hosts. Almost all warm-blooded animals can be infected. It takes various mammals as the main host. Infectious diseases are also one of the diseases that humans have not been able to effectively control....

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More