Preparation method of 6-nitrosaccharin

A technology of nitrosaccharin and nitrobenzoic acid, applied in the field of preparation of 6-nitrosaccharin, can solve the problems of difficulty in industrialization, serious environmental pollution, difficult control, etc., and achieves low price, no environmental pollution and low production cost Effect
CN101735167AActive Publication Date: 2010-06-16江苏省农用激素工程技术研究中心有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
江苏省农用激素工程技术研究中心有限公司
Publication Date
2010-06-16

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Abstract

The invention discloses a preparation method of 6-nitrosaccharin, which comprises the following steps of: adding 2-amino-4-nitrobenzoic acid into excessive methanol for carrying out reflow esterification under the catalysis of an acidic catalyst to obtain 2-amino-4-nitro methyl benzoate through postprocessing; carrying out diazotization reaction on the 2-amino-4-nitro methyl benzoate and a sodium nitrite solution in an acidic medium under the temperature of 0-20 DEG C; then adding a glacial acetic acid solution of copper chloride into a system under the temperature of 20-30 DEG C to generate 2-chloro sulfonyl-4-nitro methyl benzoate; and reacting the 2-chloro sulfonyl-4-nitro methyl benzoate with ammonia water under the temperature of 0-40 DEG C to obtain the 6-nitrosaccharin. The method has simple reaction operation, no environment pollution, wide sources and low cost of the 2-amino-4-nitrobenzoic acid as the raw material, lower production cost and suitability for industrialized production.
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Description

Technical field

[0001] The invention relates to a preparation method of organic chemical intermediates, in particular to a preparation method of 6-nitrosaccharin. Background technique

[0002] 6-Nitrosaccharin is an important chemical intermediate with a wide range of applications. It can be used in the synthetic chemical fiber industry as well as in the pesticide industry. It is an important intermediate for the synthesis of the herbicide iodosulfuron-methyl sodium salt and formamisulfuron-methyl.

[0003] US Patent No. 3158233 discloses a method for obtaining 6-nitrosaccharin from 4-nitrotoluene-2-sulfonamide as a raw material and using sodium dichromate for oxidation reaction. This process has shortcomings such as severe reaction, difficult to control, serious environmental pollution, and difficult industrialization. Summary of the invention

[0004] The purpose of the present invention is to overcome the above-mentioned problems and provide a method for preparing 6-nitrosaccha...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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