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Polyoxyethylene nonyl phenyl ether iodine complex disinfecting solution and preparation method thereof

A technology of nonylphenol polyoxyethylene ether and disinfectant, which is applied in the field of disinfectant, can solve the problems of low solubility, expensive raw materials, poor stability, etc., and achieve the effects of simple production process, good decontamination effect and improved stability

Inactive Publication Date: 2010-07-28
SHANGHAI LIKANG DISINFECTION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The most common complex of iodine and polymer compound is polyvinylpyrrolidone iodine (PVP-I), but polyvinylpyrrolidone has low solubility to iodine, the raw material is expensive, and the conditions for complexing with iodine are harsh
And other complexed iodines, such as polyethylene glycol iodine (PEG-I), polyvinyl alcohol iodine (PVA-I), alkylsulfonate complexed iodine, etc., have the disadvantages of poor stability and weak yellowing ability.

Method used

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Examples

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Effect test

preparation example Construction

[0024] The preparation method of the disinfectant solution is as follows: according to the stated content and components, heat nonylphenol polyoxyethylene ether to 50-60°C to completely melt, add iodine to stir and dissolve, and keep warm at 50-60°C for 1-3 hours , to obtain liquid A; add borax to water, stir and dissolve to obtain liquid B; while stirring, add liquid A to liquid B, and stir evenly to obtain the nonylphenol polyoxyethylene ether complex iodine disinfection liquid.

[0025] The disinfectant solution is used directly as the original solution, or diluted with water.

Embodiment 1

[0027] Heat 20 grams of nonylphenol polyoxyethylene ether-10 (TX-10) to 50-60°C to completely melt, add 2 grams of iodine and stir to dissolve, keep warm at 50-60°C for 1 hour to obtain liquid A; add 0.5 grams of borax Add it into 977.5 g of water, stir and dissolve to obtain liquid B; while stirring, add liquid A to liquid B, and stir evenly to obtain the nonylphenol polyoxyethylene ether complex iodine disinfectant.

[0028] The effective iodine content of this embodiment disinfectant is 2g / L, which can be directly used for skin and mucous membrane disinfection.

Embodiment 2

[0030] Heat 15 grams of nonylphenol polyoxyethylene ether-10 (TX-10) and 35 grams of nonylphenol polyoxyethylene ether-30 (TX-30) to 50-60 ° C to completely melt, add 5 grams of iodine and stir to dissolve, Incubate at 50-60°C for 2 hours to obtain liquid A; add 1 g of borax to 944 g of water, stir and dissolve to obtain liquid B; while stirring, add liquid A to liquid B, and stir evenly to obtain the obtained The above-mentioned nonylphenol polyoxyethylene ether complex iodine disinfectant.

[0031] The effective iodine content of this embodiment disinfectant is 5g / L, which can be directly used for skin and mucous membrane disinfection.

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Abstract

The invention relates to a polyoxyethylene nonyl phenyl ether iodine complex disinfecting solution and a preparation method thereof. The polyoxyethylene nonyl phenyl ether iodine complex disinfecting solution comprises the following ingredients in percentage by weight: 0.2 to 5 of iodine, 1 to 50 of polyoxyethylene nonyl phenyl ether, 0.05 to 1 of borax and the balance water. The preparation method of the polyoxyethylene nonyl phenyl ether iodine complex disinfecting solution comprises the following steps: heating the polyoxyethylene nonyl phenyl ether to 50 to 60 DEG C until complete fusion according to the contents and the ingredients; adding iodine to be dissolved through stirring; preserving the temperature for 1 to 3 hours at 50 to 60 DEG C to obtain a solution A; adding borax into water to be dissolved through stirring to obtain a solution B; adding the solution A into the solution B at the same time of stirring; and uniformly stirring the mixed solution to obtain the polyoxyethylene nonyl phenyl ether iodine complex disinfecting solution. The complex condition of the polyoxyethylene nonyl phenyl ether iodine complex is mild, and the preparation technology is simple. The disinfecting solution has stable property. The iodine and the polyoxyethylene nonyl phenyl ether exist in a complex state, free iodine can be released slowly, the disinfecting effect is enduring, the irritation on the skin is low, and yellow stain is not easy to occur.

Description

technical field [0001] The invention relates to a disinfectant, in particular to a complex iodine disinfectant and a preparation method thereof. Background technique [0002] Iodine is a commonly used disinfectant, which can be widely used in the disinfection of skin, mucous membranes, instruments and articles. Its bactericidal mechanism is generally believed to be based on its iodination and damage to the outer layer of cells. Free iodine can directly react with bacterial proteins and bacterial enzyme proteins, destroying the biological activity of proteins and leading to the death of microorganisms. However, elemental iodine has the disadvantages of low water solubility and high irritation, and it can also cause yellow staining. In order to overcome these shortcomings, complexes of iodine and polymer compounds have been studied to improve the properties of elemental iodine. The most common complex of iodine and high molecular compound is polyvinylpyrrolidone-iodine (PVP...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/12A01P1/00A61K33/18A61K47/48A61P31/02A61K47/60
Inventor 张万国张忠敏葛莉娟
Owner SHANGHAI LIKANG DISINFECTION HIGH TECH
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