Application of ginsenoside Rb3 in preparing medicines for treating depressive disorder

Abstract

The invention belongs to the field of medicine or natural medicine chemistry, and particularly relates to application of a natural product-ginsenoside Rb3 in preparing a medicine for treating depressive disorder. In the application, ginsenoside Rb3 is directly extracted and obtained from panax notoginseng, ginseng or American ginseng; the dosage is 3.0-20.0mg per kilo of weight each day. Through organically regulating in vivo neurotransmitter and neural network balance and actions of multiple ways and multiple targets such as promoting nerve growth and the like, ginsenoside Rb3 is applied in preparing medicine for treating depressive disorder, so that obvious anti-depression effect is obtained. In addition, ginsenoside Rb3 can be extracted and obtained through traditional Chinese medicine or natural plants, and can be supplied for patients with depressive disorder to be continuously taken for a long period. The ginsenoside Rb3 has clear effective substance, obvious therapeutic effect, small toxic or side effect and definite action mechanism, and is in favor of radically treating depressive disorder and avoiding recurrence of depressive disorder.

Description

technical field [0001] The invention belongs to the field of medicine or natural medicinal chemistry, and in particular relates to the application of a natural product in the preparation of medicines for treating depression. Background technique [0002] Depression is a common mental illness. The so-called Depressive Disorder refers to a mood disorder syndrome characterized by low mood. It usually manifests as long-term low mood, grief, and loss of interest. , self-blame and low self-esteem, slow thinking, slow action, listlessness, loss of appetite, and even extreme self-harm thoughts such as suicide in severe cases. Depression is a disease with high incidence, high recurrence rate, high disability rate and high burden rate. According to the statistics of the World Health Organization, depression has become the fourth largest disease in the world, and it is predicted that by 2020, it may become the second largest disease in the world after coronary heart disease. Depressi...

AI Technical Summary

Problems solved by technology

Chinese patent 200610027507.1 discloses that protopanaxadiol can be used as an active ingredient in the preparation of antidepressant drugs. Subsequently, in order to further study and improve the application of this type of compound in the preparation of antidepressant drugs, the application number 200610116353.3 further discloses a class of protopanaxadiol Alcohol derivatives have antidepressant activity when applied as a single component. Compared with protopanaxadiol, these derivatives contain specific derivative groups, which are beneficial to enhance the antidepressant effect. However, these protopanaxadiol derivatives are Obtained by artificial synthesis, although experiments have proved that these protopanaxadiol derivatives have antidepressant effects, the degree of effectiveness of their curative effect and whether they bring other negative effects at the same time are still an unknown problem

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