Method for preparing microcapsule taking hydrophobic substance as core material by complex coacervation method

A technology of composite coacervation and hydrophobic substances, which is applied in the field of preparing microcapsules, can solve the problems of high price, low stability, and large differences, and achieve the effects of uniform particle size, easy control of distribution, and good spherical shape

Inactive Publication Date: 2012-07-25
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Gum Arabic is secreted from the trunks of Acacia trees and Acacia trees. Due to the limitation of the origin of such plants, Gum Arabic can only rely on imports, and the price is high. At the same time, the characteristics of plant sources make it different brands and different batches. There is a large difference between them, and the stability is not high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Weigh 7.2 g of gelatin and 0.8 g of carboxymethyl cellulose, add 800 ml of deionized water, and stir and dissolve in a 60° C. water bath. Weigh 8g of cinnamaldehyde, add it to the wall material solution, disperse and homogenize at high speed for 2 minutes. The speed of the disperser is 10000r / min. Stir at a constant temperature of 45 °C, and the stirring speed is 400 r / min. 10% acetic acid solution was added to adjust the pH to 4.6, and the reaction was stirred for 5 minutes. Use an ice-water bath to cool to below 15°C. The pH was adjusted to 6.0, transglutaminase was added, the enzyme activity was 100 U / g, and the dosage was 1 / 4 of the mass of gelatin. Stir at medium speed at room temperature for 4 to 6 hours.

[0032] The microcapsules prepared under the conditions have better spherical shape, smooth wall membrane and uniform particle size, and can well embed the core material cinnamaldehyde in the capsules. The yield of microcapsules was 85.95% and the efficienc...

Embodiment 2

[0034] Weigh 7.2 g of gelatin and 0.8 g of carboxymethyl cellulose, add 800 ml of deionized water, and stir and dissolve in a 60° C. water bath. Weigh 16 g of cinnamaldehyde, add it to the wall material solution, and disperse and homogenize at high speed for 3 minutes. The speed of the disperser is 10000r / min. Stir at a constant temperature of 45 °C, and the stirring speed is 400 r / min. 10% acetic acid solution was added to adjust the pH to 4.6, and the reaction was stirred for 5 minutes. Use an ice-water bath to cool to below 15°C. Adjust the pH to 6.0, add transglutaminase, the enzyme activity is 100U / g, and the dosage is 1 / 4 of the mass of gelatin. Stir at medium speed at room temperature for 4 to 6 hours.

[0035] Compared with Example 1, the amount of cinnamaldehyde embedded in the microcapsules prepared under this condition was greatly increased. The yield of microcapsules was 97.01% and the efficiency was 86.55% measured by ethanol extraction-ultraviolet spectropho...

Embodiment 3

[0037] Weigh 7 g of gelatin and 1 g of carboxymethyl cellulose, add 800 ml of deionized water, and stir to dissolve in a 60°C water bath. Weigh 8g of cinnamaldehyde, add it to the wall material solution, disperse and homogenize at high speed for 2 minutes. The speed of the disperser is 10000r / min. Stir at a constant temperature of 45 °C, and the stirring speed is 400 r / min. 10% acetic acid solution was added to adjust the pH to 4.4, and the reaction was stirred for 5 minutes. Use an ice-water bath to cool to below 15°C. Adjust the pH to 6.0, add transglutaminase, the enzyme activity is 100U / g, and the dosage is 1 / 4 of the mass of gelatin. Stir at medium speed at room temperature for 4 to 6 hours.

[0038]The yield of microcapsules was 81.6% and the efficiency was 73.26% as measured by ethanol extraction-ultraviolet spectrophotometry. The encapsulation rate of microcapsules decreased when the gelatin / carboxymethylcellulose ratio deviates from the optimal value.

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Abstract

The invention relates to a method for preparing a microcapsule taking a hydrophobic substance as a core material by a complex coacervation method. The method has the advantages of simple process and relatively lower cost, and the product has relatively higher encapsulation efficiency. The method comprises the following steps of: (1) weighing gelatin and carboxymethylcellulose in certain proportion, and stirring and dissolving the gelatin and the carboxymethylcellulose in hot water; (2) adding hydrophobic substance in certain mass ratio and dispersing the hydrophobic substance for 2 minutes ata high speed to form emulsion; (3) stirring the emulsion at the constant temperature of 45 DEG C, adjusting the pH of the emulsion to be 4.4 to 4.8 with a 10 percent ethylic acid and reacting the emulsion with the ethylic acid for 5 minutes; (4) cooling the emulsion until the temperature is below 15 DEG , adjusting the pH of the emulsion to be 6.0 and adding glutamine transaminase for solidification; and (5) filtering the mixed solution to obtain a wet microcapsule product, and freeze-drying or spray-drying the wet microcapsule product to obtain a dried microcapsule product.

Description

technical field [0001] The invention relates to the food and flavor and fragrance industries, in particular to a technology for initiating complex coagulation reaction by adjusting pH, embedding core materials and preparing microcapsules. The selected core material is a hydrophobic substance, which can be an oil-soluble essence, such as cinnamaldehyde, sweet orange oil, peppermint oil, etc., or a functional substance, such as fish oil, VE, etc. Background technique [0002] The main functions of microencapsulation are: (1) to improve the physical properties of substances, liquid substances can be turned into solid powder after microencapsulation, which is convenient for storage and transportation, and also easy to add to food. This is very important for hydrophobic substances that are usually oily and have poor dispersibility; (2) to improve the stability of the substance, the microencapsulation technology separates the core material from the surrounding environment, avoidin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L89/00C08L1/26C08K5/07C08K5/1545C08K5/00B01J13/10
Inventor 张晓鸣张海洋吕怡倪悦夏书芹贾承胜
Owner JIANGNAN UNIV
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