Intravascular photoacoustic and ultrasonic double-mode imaging endoscope device and imaging method thereof
A dual-mode imaging and endoscope technology, applied in catheters, medical science, sensors, etc., can solve the problem of shallow penetration depth and achieve the effect of convenient use and small size
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Embodiment 1
[0034] Example 1: A dual-mode endoscopic imaging device for intravascular photoacoustic ultrasound (structural schematic diagram as shown in figure 1 shown)
[0035]The device includes a miniature photoacoustic ultrasound dual-mode imaging endoscopic probe 1, a photoacoustic excitation light source generator 2, an ultrasonic signal excitation and acquisition component 3, and a computer 4 with acquisition control software and image reconstruction software; the miniature photoacoustic ultrasound A dual-mode imaging endoscopic probe 1, a photoacoustic excitation light source generator 2, an ultrasonic signal excitation and acquisition component 3, and a computer 4 with acquisition control software and image reconstruction software are electrically connected in sequence; the miniature photoacoustic ultrasonic dual-mode imaging The peeping probe 1 is composed of an incident optical fiber 5, a hollow circular ring array ultrasonic probe 6, a coating tapered high reflection mirror 7,...
Embodiment 3
[0044] Application of the device described in Example 1 to realize photoacoustic and ultrasonic endoscopic imaging of the cross-section of the vascular lumen
[0045] (1) Insert a miniature photoacoustic ultrasound dual-mode imaging endoscopic probe (1.3 mm in diameter) into the lumen of the isolated rabbit abdominal aorta;
[0046] (2) Photoacoustic excitation, photoacoustic collection, and ultrasonic excitation and collection: a fiber laser (Brilliant B, Bigsky) pumped by Nd:YAG is used, the output laser wavelength is 1064nm, the pulse width is 8ns, and the repetition frequency is 20HZ; The pulsed laser (with a wavelength range of 1000nm) generated by the exciter is coupled through the incident optical fiber, and is uniformly incident on the wall of the blood vessel laterally through the coated conical high-reflection mirror to excite the blood vessel wall to generate photoacoustic signals; the hollow ring array ultrasonic detection After receiving the photoacoustic signal, ...
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