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Novel skin radiation injury protective agent

A radiation damage and protective agent technology, applied in the field of traditional Chinese medicine and bioengineering drugs, can solve the problems of lack of skin radiation damage protection and treatment, prone to ulcers, and difficult to heal.

Inactive Publication Date: 2010-12-22
江其生
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AI Technical Summary

Problems solved by technology

After the skin is irradiated with a certain dose, there will be local blood supply disorder, ischemia and necrosis of tissue cells, poor regeneration and repair ability, and ulcers are prone to occur, and once an ulcer is formed, it is difficult to heal
However, there is still a lack of ideal drugs for the protection and treatment of skin radiation damage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0025] The diagnostic criteria for radiation injury, the application method and experimental results of skin radiation injury protective agent are as follows:

[0026] 1. Radiation injury diagnostic criteria

[0027] The International Union Against Cancer (UICC) divides skin radiation damage into grade IV: grade 0: no change; grade 1: follicles, mild erythema, alopecia, dry dermatitis, decreased sweating; grade 2: obvious erythema, macular wetness Dermatitis, moderate edema; Grade 3: confluent wet dermatitis, pitting edema; Grade 4: necrosis, ulceration, hemorrhage.

[0028] 2. Therapeutic effect of skin radiation injury protective agent on patients with skin radiation injury

[0029] Selected and observed 60 malignant tumor patients receiving radiotherapy, including 26 cases of nasopharyngeal carcinoma and 34 cases of lung cancer, aged 52-65 years, with an average age of 58.5 years. Randomly divided into a protection group of 30 cases (male 18 cases, female 12 cases) and a ...

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Abstract

The invention relates to the fields of traditional Chinese medicines and bioengineering medicines, particularly a novel skin radiation injury protective agent which is capable of preventing and treating skin radiation injury and combines the traditional Chinese medicines with bioengineering medicines. The protective agent is prepared from traditional Chinese medicines, which have the functions of clearing away heat and toxic material, activating blood circulation to dissipate blood stasis, removing saprophytic muscle, nourishing the blood, moisturizing the skin and the like, and cell growth factor, which can promote epithelial cell growth and reproduction, and wound healing; and thus, the protective agent has the functions of preventing skin radiation injury, promoting injured skin to quickly heal, reducing the formation of scar tissues, and the like. The protective agent can be used for preventing and treating skin radiation injury of tumor radiotherapeutic patients and treating various clinic skin injuries (burnt, hurt, frostbite and the like), and can also be used for treating skin radiation injury caused by nuclear and radiation accidents, terrorist attacks and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine and bioengineering medicine, in particular to a novel skin radiation injury protective agent developed by combining traditional Chinese medicine and modern bioengineering medicine, which can prevent and treat skin radiation injury. Background technique [0002] According to the statistics of the World Health Organization (WHO) and the American Society of Clinical Oncology (ASCO), there are about 10 million new cancer patients in the world every year, and 1.6 million new cancer patients in my country every year. Patients undergoing radiotherapy will cause different degrees of radiation damage to the skin, manifested as: erythema, itching, dry dermatitis, follicles in the irradiation field in the acute stage, followed by wet dermatitis, etc. In severe cases, secondary infection may even form refractory ulcers , the patient is very painful and may affect the smooth progress of radiation ther...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K36/704A61P17/16A61P17/02
Inventor 江其生
Owner 江其生
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