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Aquilaria sinensis fruit skin extract and preparation method and application thereof

A technology for the peel and extract of Akiras sinensis, which is applied in the fields of plants, traditional Chinese medicine and natural medicine, and can solve the problems of less development and utilization of fruit resources, and achieve the effects of rich raw materials, broad-spectrum antibacterial activity, improved utilization rate and economic benefits

Active Publication Date: 2011-03-30
GUANGDONG INST OF MICROORGANISM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the development of other tissues of A. chinensis mainly focuses on the extraction and application of the volatile oil components of leaves and seeds, but there is little development and utilization of its fruit resources. Only the application of A. chinensis fruit and its extracts in the preparation of antitumor drugs has been reported. , but there is no report on the pharmacological activity of the antibacterial effect of Akiba

Method used

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  • Aquilaria sinensis fruit skin extract and preparation method and application thereof
  • Aquilaria sinensis fruit skin extract and preparation method and application thereof
  • Aquilaria sinensis fruit skin extract and preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0014] Embodiment 1: adopt cold dipping extraction method:

[0015] Take 3g of the fruit peel of Akiras sinensis, crush it, add 200ml of chloroform, cold soak at room temperature for 24h, filter, add 200ml of chloroform to the filter residue, cold soak at room temperature for 24h, filter, combine the two filtrates, Concentrate and dry under reduced pressure to obtain the extract of Akiras radiata peel.

Embodiment 2

[0016] Embodiment 2: adopt reflux extraction method:

[0017] Take 5g of the fruit peel of Akiras sinensis, crush it, then add 100ml of petroleum ether, extract under reflux at 60°C for 2h, filter, then add 100ml of petroleum ether to the filter residue, extract under reflux at 60°C for 2h, filter, combine the filtrates, reduce Concentrate to dryness under pressure to obtain the extract of Akiras radiata peel.

Embodiment 3

[0018] Embodiment 3: adopt ultrasonic extraction method:

[0019] Get 5g of Akiras radiata pericarp, pulverize it, then add volume fraction and be 70% ethanol aqueous solution 100ml, be ultrasonic 30min under the frequency of 40KHZ, filter, then add volume fraction in the filter residue and be 70% ethanol aqueous solution 100ml, at frequency 40KHZ Sonicate at 40KHZ for 30 minutes, filter, combine the filtrates, and concentrate to dryness under reduced pressure to obtain the extract of Akiras radiata peel.

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Abstract

The invention discloses an aquilaria sinensis fruit skin extract, a preparation method thereof and application thereof. The method comprises the following steps of: crushing aquilaria sinensis fruit skin serving as a raw material, adding water, ethanol, ethanol water, ethyl acetate, trichloromethane or petroleum ether serving as a solvent, performing reflux extraction, ultrasonic extraction or cold extraction to obtain extracting solution, and performing concentration drying under reduced pressure or freeze drying on the extracting solution to obtain the aquilaria sinensis fruit skin extract. The aquilaria sinensis fruit skin extract has broad-spectrum antimicrobial activity, so that the extract can be applied to a food preservative and the preparation of antibacterial medicaments or antifungal medicaments. The aquilaria sinensis fruit skin extract has a simple preparation method, low costs and abundant raw materials. Therefore, the utilization rate and economic benefit of aquilaria sinensis are improved.

Description

Technical field: [0001] The invention belongs to the fields of plants, traditional Chinese medicines and natural medicines, and in particular relates to an extract from the peel of arborina chinensis, a preparation method and application thereof. Background technique: [0002] There are more than 15 species of Aquilaria (Thymelaeaceae) in the world, most of which are distributed in India, Malaysia, Vietnam and other places. There is only one species of Aquilaria in my country, namely Aquilaria sinensis (Lour.) Gilg]. It is a rare and endangered medicinal plant unique to our country. It is mainly distributed in Guangdong, Guangxi, Hainan, Fujian and other regions. Its resin is customarily called domestic agarwood, earth agarwood or Guanxiang. It has a wide range of uses and high medicinal value. It has the effects of promoting qi and relieving pain, warming the middle and relieving vomiting, inducing qi and relieving asthma. The application of traditional Chinese medicine to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A23L3/3472A61P31/04A61P31/10A61K131/00
Inventor 李浩华章卫民陈玉婵王磊
Owner GUANGDONG INST OF MICROORGANISM
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