Chinese patent medicine (Bezoar Qianliekang Turunda) for treating prostate disease and preparation method thereof

A technology of Niuhuangqianliekang and traditional Chinese medicine preparations, applied in the field of medicine and chemical industry, can solve the problems of difficulty in penetrating the prostate capsule, small effect on the lesion, waste of drugs, etc., and achieves the effect of inhibiting experimental bacterial prostatitis, good for clearing heat, and small dosage.

Active Publication Date: 2012-01-18
WUHAN JIANMIN DAPENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the unique anatomical location of the prostate, after oral administration or intramuscular injection, the dose of the drug is very small after reaching the site, and it is difficult to penetrate the prostate capsule, so the effect on the lesion is very small, and the therapeutic effect is minimal
Since prostatitis mostly has a long course of disease and complex etiology, for bacterial prostatitis, no matter what form of western medicine anti-inflammatory is used, it can only be effective in a short period of time. Over time, bacteria develop resistance to western medicine, and the efficacy will be obvious Reduced, and antibacterial drugs do n

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0027] In vitro cultivation of Calculus Calculus 14g, Phellodendron Phellodendron 400g, Scutellaria baicalensis 350g, Rhizome 350g, Salvia miltiorrhiza 300g, frankincense (manufactured) 55g, borneol 19g. Take the four flavors of Phellodendron Phellodendri, Scutellaria baicalensis, Fenugreek, and Salvia miltiorrhiza, add 70% ethanol to heat and reflux to extract twice, add 5 times the amount of 70% ethanol for the first time, extract for 2 hours, add 3 times the amount of 70% ethanol for the second time, extract 1 hours, combine the filtrates, reclaim ethanol under reduced pressure until there is no ethanol smell, concentrate to an extract with a relative density of 1.15 to 1.20 (80°C heat measurement), spray dry, collect dry extract powder, and set aside; Grind finely, sieve (120 mesh) respectively, and set aside; take frankincense, seal and freeze, quickly crush into the finest powder, and sieve (120 mesh). Separately take 1100 g of mixed fatty acid glycerides, add 14.4 g of ...

example 2

[0029] In vitro cultivation of bezoar 15g, Phellodendron 450g, Scutellaria baicalensis 400g, Rhizome 400g, Salvia miltiorrhiza 350g, frankincense (made) 60g, borneol 20g. Take the four flavors of Phellodendron Phellodendron, Scutellaria baicalensis, Fenugreek, and Salvia miltiorrhiza, add 70% ethanol to heat and reflux to extract twice, add 6 times the amount of 70% ethanol for the first time, extract for 2.5 hours, add 4 times the amount of 70% ethanol for the second time, extract 1.5 hours, combine the filtrates, reclaim ethanol under reduced pressure until there is no ethanol smell, concentrate to an extract with a relative density of 1.15 to 1.20 (80°C heat measurement), spray dry, collect dry extract powder, and set aside; Grind finely, sieve (120 mesh) respectively, and set aside; take frankincense, seal and freeze, quickly crush into the finest powder, and sieve (120 mesh). Separately take 1191g of mixed fatty acid glycerides, add 15.4g of polysorbate 80 (Tween 80), hea...

example 3

[0031] In vitro cultured bezoar 16g, Phellodendron 500g, Scutellaria baicalensis 450g, Rhizome 450g, Salvia miltiorrhiza 400g, frankincense (manufactured) 65g, borneol 21g. Take the four flavors of Phellodendron Phellodendron, Scutellaria baicalensis, Fenugreek, and Salvia miltiorrhiza, add 70% ethanol to heat and reflux for extraction twice, add 7 times the amount of 70% ethanol for the first time, extract for 3 hours, add 5 times the amount of 70% ethanol for the second time, extract 2 hours, combine the filtrates, reclaim ethanol under reduced pressure until there is no ethanol smell, concentrate to an extract with a relative density of 1.15 to 1.20 (80°C heat measurement), spray dry, collect dry extract powder, and set aside; Grind finely, sieve (120 mesh) respectively, and set aside; take frankincense, seal and freeze, quickly crush into the finest powder, and sieve (120 mesh). Separately take 1282g of mixed fatty acid glycerides, add 16.4g of polysorbate 80 (Tween 80), h...

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Abstract

The invention discloses a Chinese materia medica preparation (Bezoar Qianliekang Turunda) for treating prostate disease and a preparation method thereof. The Chinese materia medica preparation is prepared from the following traditional Chinese medicinal materials in parts by weight: 14-16 parts of cultured calculus bovis, 400-500 parts of phellodendron bark, 350-450 parts of baical skullcap, 300-400 parts of root of red rooted salvia, 350-450 parts of rhizoma dioscoreae hypoglaucae, 19-21 parts of borneol, 55-65 parts of frankincense,1100-1282 parts of mixed fatty acid glyceride and 14.4-16.4 parts of polysorbate 80 (Tween 80). The Chinese materia medica preparation (Bezoar Qianliekang Turunda) for treating prostate disease has the efficacies of clearing away heat and toxic material, promoting blood circulation to stop pain, removing dampness by diuresis and treating stranguria, and can be used for treating the symptoms of frequent micturition, urgency of micturition, dysuria, difficulty in micturition, burning heat sensation in urethra, dripping discharge of urine, pain in the lower abdomen, pain in the perineum, pain in the spermary and the like caused by prostatitis. The production process is scientific and the product quality is stable, safe and reliable.

Description

1. Technical field: [0001] The invention belongs to the technical field of medicine and chemical industry, and particularly relates to a traditional Chinese medicine preparation for treating prostate diseases and a preparation method thereof. 2. Background technology: [0002] Prostate disease is a common and frequently-occurring disease in men. It has the characteristics of many types of diseases, high incidence, and long duration of onset. According to domestic statistics, its incidence accounts for 35-40% of adult men, and it has an increasing trend year by year. Many inconveniences. At present, there are many drug options for the treatment of prostate diseases, but the curative effect is not satisfactory, and the recurrence rate is high. [0003] In the prior art, there are: oral administration of Chinese medicine decoction, oral administration of Chinese patent medicine, sitz bath of Chinese medicine, rectal administration of Chinese medicine suppository, enema of Chi...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/02A61K47/34A61P13/08A61K31/045A61K35/413A61K47/14A61K47/26
Inventor 郭庆华徐念明陈华曦骆小梅蔡红娇
Owner WUHAN JIANMIN DAPENG PHARMA
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