Human diploid cell rabies vaccine virus seed and preparation method thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ZHEJIANG PUKANG BIOTECH
- Publication Date
- 2013-05-01
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Abstract
Description
technical field
[0001] The invention relates to the field of biotechnology, in particular to using human diploid cells (KMB17) to produce vaccine virus seeds for preventing human rabies and a preparation method thereof. Background technique
[0002] Rabies is a disease caused by the rabies virus, once the onset, 100% fatal. In recent years, the rabies epidemic in my country has continued to rise, and the incidence rate is now the second in the world, second only to India. The number of deaths from rabies ranks first among the 37 legally notifiable infectious diseases. Rabies cannot be cured so far but can be effectively prevented, so the prevention of rabies in our country is particularly important.
[0003] At present, the culture substrate cells used in the production of rabies vaccine in the world mainly include animal-derived cells such as hamster kidney cells, chicken embryo cells and African green monkey kidney cells (Vero cells). Animal-derived primary cells cannot ...