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Medicament for treating insulin resistance of type 2 diabetes

A technology for insulin resistance and type 2 diabetes, applied in drug combination, metabolic diseases, pharmaceutical formulations, etc., can solve the problems of lack of large-scale clinical research in traditional Chinese medicine compound research, not meeting the requirements of clinical evidence-based medicine, and enhancing credibility. Achieving the effect of low price, few adverse reactions and alleviating symptoms

Inactive Publication Date: 2011-07-06
SHANXI PROVINCE CHINESE MEDICINE RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine has broad prospects for the treatment of insulin resistance, but there are still considerable deficiencies: research on compound Chinese medicine lacks large-scale clinical research, does not meet the requirements of clinical evidence-based medicine, and its credibility needs to be strengthened; lack of comparative studies with insulin sensitizers reduces persuasiveness Wait

Method used

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  • Medicament for treating insulin resistance of type 2 diabetes
  • Medicament for treating insulin resistance of type 2 diabetes
  • Medicament for treating insulin resistance of type 2 diabetes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Crush 210g of Radix Astragali into fine powder for later use. Take 210g of astragalus, 210g of sealwort, 140g of cocoon, 210g of ghost arrow feather, 168g of coptis, add 7.5Kg of water, and cook for 1.5h. Repeat the above steps three times, combine the decoction, filter, concentrate the filtrate into a thick paste with a relative density of 1.28 (85°C), add fine powder of Astragalus membranaceus, mix well, dry, pulverize, put into capsules, and make capsule Yiqihua Cloudy capsules.

Embodiment 2

[0021] Crush 150g of Radix Astragali into fine powder for later use. Take 150g of astragalus, 200g of sealwort, 150g of cocoon, 150g of ghost arrow feather, and 150g of coptis, add 6.4Kg of water, and cook for 2 hours. Repeat the above steps three times, combine the decoction, filter, concentrate the filtrate into a thick paste with a relative density of 1.30 (60°C), add astragalus fine powder, mix well, dry, crush, add appropriate amount of auxiliary materials, mix well, and make granules, Compressed into tablets.

Embodiment 3

[0023] Crush 210g of Radix Astragali into fine powder for later use. Take 210g of astragalus, 200g of sealwort, 150g of cocoon, 200g of ghost arrow feather, 150g of coptis, add 9.1Kg of water, and decoct for 1 hour. Repeat the above steps three times, combine the decoction, filter, concentrate the filtrate into a thick paste with a relative density of 1.32 (85°C), add astragalus fine powder, mix well, dry, pulverize, add appropriate amount of auxiliary materials, mix well, and make concentrated pills , dry and polish.

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Abstract

The invention relates to a medicament for treating insulin resistance of type 2 diabetes. Active constituents of the medicament are obtained by the steps of taking 30-40 parts of astragalus root, 15-20 parts of polygonatum, 14-18 parts of coptsir root, 15-20 parts of winged euonymus twig and 10-15 parts of silkworm moth cocoon as pharmaceutical materials, smashing half parts by weight of the astragalus root into fine powder, decocting the other pharmaceutical materials and the remaining astragalus root three times by adding water, concentrating a decoction liquid into thick paste with relative density of 1.26-1.33, adding the fine powder of the astragalus root into the thick paste, and uniformly mixing. According to a pharmacodynamic test and a clinical test, the medicament disclosed by the invention has effects of invigorating qi, nourishing yin, activating blood circulation and dissipating blood stasis and can be used for improving the insulin resistance, reducing blood sugar, correcting metabolic disorder, relieving unpleasant symptoms and improving life quality, thereby being an effective medicament for treating the insulin resistance of the type 2 diabetes.

Description

technical field [0001] The invention relates to a medicine for treating insulin resistance of type 2 diabetes, in particular to a medicine for treating insulin resistance of type 2 diabetes prepared by using traditional Chinese medicine as a raw material medicine. Background technique [0002] Insulin resistance refers to the insufficiency of insulin to perform its normal biological effects, manifested as the impairment of glucose utilization by peripheral tissues, especially muscle and adipose tissue. Early islet β cells can compensatory increase insulin secretion to make up for its lack of effect, but over time, the function of islet β cells will gradually fail, leading to abnormal glucose tolerance and diabetes. Insulin resistance is not only the main pathogenesis of type 2 diabetes, but also a common risk factor for many diseases such as obesity, hypertension, coronary heart disease and cerebrovascular disease, which brings extremely serious damage to the body. Therefor...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P3/10A61P5/50A61K35/64
Inventor 郭俊杰
Owner SHANXI PROVINCE CHINESE MEDICINE RES INST
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