42results about How to "Correct metabolic disorders" patented technology

The invention discloses a food composition applicable to a diabetic. The food composition comprises the following components: tartary buckwheat, black rice, lotus roots, coix seeds, rice, oats, Chinese yams, lotus seeds, yellow corns, hazelnuts, garbanzos, rice beans, konjak, black sesame, sweet almonds, shii-take, medlar, dried mulberries, dried seedless grapes, fermented black beans, kudzu vine root powder, wheat germ powder, cinnamon powder, hawthorn powder, carrot powder, tomato powder, pumpkin powder, concentrated whey protein, camellia oil, perilla seed oil, corn oil, maltodextrin, L-carnitine, L-malic acid, xylitol and milk calcium. The invention further discloses a preparation method of the food composition applicable to the diabetic. Through reasonable formula ratio, the food composition can not only control the blood sugar, but also lose weight, improve the insulin resistance, lower the blood pressure, improve the blood lipid, prevent or delay occurrence and development of complications and improve the living quality and the health level of the diabetic.

A health-care food for diabetics is prepared from balsam pear (30-99 wt.%) and ginseng powder (rest). Its advantages are high effect to regulate blood sugar bidirectionally and high safety.

The invention provides an expression method of a human globular adiponectin-glucagon-like peptide-1 analog (gAd-GLP-1-A) peptide fusion protein. The method comprises the following steps of: constructing a prokaryotic expression vector containing human gAd-GLP-1-A fusion genes, converting Escherichia coliBL21 (DE3), obtaining a gAd-GLP-1-A fusion protein containing 6*His tag from an inclusion body by inducible expression, and further digesting the gAd-GLP-1-A fusion protein by using enterokinase to obtain the protein. Animal research shows that the fusion protein has remarkable activity of reducing blood sugar. The fusion protein can promote pancreas islet beta cells to secrete insulin, improve the insulin resistance and remarkably correct the internal metabolic disturbance of type-2 diabetes, and can be applied to preparation of medicaments for treating the type-2 diabetes.

Disclosed is an adiponectin-Glucagon-like peptide-1-like peptide recombinant protein expression vector and construction, wherein adiponectin and GLP-1-A encoded gene are obtained by utilizing PCR technology, the method comprises obtaining adiponectin through amplification of adiponectin spherical domain gene, then obtaining GLP-1-A encoded gene by mutating codons encoding No. 8 amino acid alanine in GLP-1-(7-37) encoded gene, then cloning GLP-1-A and adiponectin encoded genes directionally to expression vector by utilizing enzyme digestion technology, obtaining adiponectin-glucagon-like peptide-1 analogue peptide fusion protein expression vector, finally expressing adiponectin-GLP-1-A fusion protein through transforming protein expression bacteria.

The invention relates to a medicine for treating hashimoto thyroiditis. The medicine is prepared to a conventional oral preparation from the following components in parts by weight: 30-40 parts of astragalus membranaceus, 15-20 parts of radix curcumae, 15-25 parts of moutan barks, 15-20 parts of curcuma zedoary, 15-20 parts of thunberg fritillary bulb and 30-40 parts of turtle shells. The medicine provided by the invention has the functions of managing Qi and activating blood and reducing phlegm and resolving masses. Pharmacodynamic test and clinical and trial study verify that the medicine provided by the invention not only can reduce the antibody of hashimoto thyroiditis to correct metabolic disorders, but also can relieve unwell symptoms to improve the living quality. The medicine is remarkable in effect of treating hashimoto thyroiditis.

The invention discloses a body-beautifying flammukinan health capsule, comprising the components by weight percent: 20-30 percent of flammukinan, 50-80 percent of flammukinan by-product, 20-60 percent of lentinan, 40-80 percent of lentinan by-product and 2-10 percent of lotus leaf, 2-10 percent of hawthorn, 2-10 percent of Chinese waxgourd peel and 2-10 percent of coix seed dried fine powder. The body-beautifying flammukinan health capsule contains the main components of flammukinan and lentinan, can be stored under normal temperature, can reduce blood fat and blood viscosity, correct disorder of lipoid metabolism, improve the physiological activities of the organism, enhance fat consumption, and have the effects of promoting blood circulation and removing blood stasis, promoting digestion and dissolving mass, and reducing fat and promoting diuresis. The capsule is applicable to fatness of obesity caused by high blood pressure patients and high blood fat, is also applicable to the patients with fatty liver and alcohol liver, and can achieve good body-shaping effect by long-term use matched with movement.

The invention discloses an application of naja atra venin to preparation of a medicament for treating diabetes and a diabetic nephropathy complicating disease. As proved by animal experiments, after the total toxicity of naja atra venin which is modified and renatured physically in a range of 10-3,000 mug / kg is applied, the weight of a mouse suffering from diabetic nephropathy can be reduced, the blood sugar level of a mouse suffering from diabetes can be lowered, urokinase proteins are reduced, plasma albumin is raised, blood plasma triglyeride is reduced, plasma creatinine and urea nitrogen are reduced, the expression of inflammatory factors in kidney is reduced, the oxidative stress level is lowered, glomerulosclerosis is reduced, and nephridial tissue and islet injury are relieved.

The invention discloses an integrated alcoholic beverage, which comprises base liquor and additives, and is characterized by comprising 70-80 percent of base liquor and 20-30 percent of additives, wherein the base liquor is distilled liquor; the additive comprise extracts of the following medicinal materials in parts by weight: 20-50 parts of platycodon root, 20-60 parts of cinnamon, 15-50 parts of lily, 15-80 parts of medlar, 10-80 parts of lotus seed, 20-100 parts of hawthorn, 20-80 parts of coix seed and 10-50 parts of malt. The additives have various effects of nourishing, treatment and the like and meet the principle of monarch, minister, assistant and guide of Chinese medicine, so that the integrated alcoholic beverage has complete functions and quick response. A product provided by the invention has the effects of enhancing resistance, invigorating the circulation of blood, enriching the blood, adjusting a human immunologic mechanism, correcting in-vivo metabolism, eliminating fatigue, softening blood vessel and resisting aging and can be used as an auxiliary therapeutic agent of some tumors, senile diseases, urinary diseases, gynecological diseases, traumatic injury and iron deficiency anemia.

The invention relates to a female radish (male barren radish) freeze-dried powder, relating to a freeze-dried powder, more in particular to a female radish freeze-dried powder. The invention provides a female radish freeze-dried powder which is long in preservation time, rich in nutrition and easy to be absorbed by human body. In the invention, the female radish freeze-dried powder is prepared byusing female radish as main raw material.

The invention relates to a compound recipe kidney-strengthening tablet for enlivening the spleen and strengthening kidney in the traditional technique field. The preparing method comprises the following steps: disintegrating rhubarb horsetails into the powder; collating after immersing; collecting the collation liquid; disintegrating radix salvia miltiorrhiza, astragalus root, extractum glycyrrhizae liquidum and hirudo into the powder; extracting with alcohol reflux; filtering; merging the filtering liquid and the collation liquid; mixing uniformly; concentrating into the dense plaster; getting the extract of five tastes medicine; adding fermenting Cordyceps sinensis bacterial powder, crystalline cellulose, sodium carboxymethylstarch, starch and dolomol; mixing uniformly; getting the product by pelleting. The invention can reduce BUN and SCr level, which improves plasma protein content, improves the nutrient state, accelerates the renovation and the reactivation of nephric tubule epithelial cell, corrects the metabolic disorder of amino acid, protein and lipid, adjusts the cell immunity, improves the immunity, protects and recovers the kidney function, and prevents secondary infection.

The invention discloses a compound formula for preventing and treating hyperhomocysteinemia (HHcy) by comprehensively correcting metabolic disorders. The compound formula includes the components of 300-1000 mg / d of glycine betaine, 500-2000 mg / d of calcium gluconate, 10-40 mg / d of folic acid, 5-15 mg / d of a vitamin B2, 5-15 mg / d of a vitamin B6, 20-80 [mu] g / d of a vitamin B12 and 10-50 mg / d of alpha-tocopherol. According to the formula, symptomatic prevention and treatment and cause prevention and treatment are integrated, and in the symptomatic aspect, target damage in a high homocysteine (Hcy) state of a current body is eliminated by relieving ROS damage and vascular endothelial cell viability reduction; in the cause aspect, the purpose of quickly reducing the blood Hcy level is achieved by comprehensively correcting five biochemical pathways involved in the folate metabolism disorder; in addition, a high-throughput cell experiment and a random double-blind control multi-center volunteer experiment are comprehensively utilized in formula development; and the action range and a toxicity threshold value of each component in the formula are accurately detected, so that the use dosage of each component has certain tolerance and extremely high safety, and the compound formula is suitable for serving as a core formula of a health care product or a dietary therapy nutritional supplement, and is beneficial to development and marketing of subsequent related products.

The invention relates to a composition for reducing blood glucose and blood lipid and preventing and / or treating diabetes mellitus and complications thereof and application of the composition. The composition in a formula comprises, by weight, 20%-75% of herba houttuyniae, 15%-70% of prunus persica and 10%-30% of cortex phellodendri. The composition and the application have the advantages that good curative effects can be realized by the composition for preventing and treating the diabetes mellitus, type 2 diabetes mellitus in particular, high blood lipid and the diabetes complications, and side effects rarely can be realized; the composition can be used for preparing medicines for reducing the blood glucose and the blood lipid and preventing and / or treating the diabetes mellitus and the complications of the diabetes mellitus and also can be used for preparing healthcare products for reducing the blood glucose and the blood lipid and preventing the diabetes mellitus and the complications of the diabetes mellitus.

The invention discloses a food suitable for a diabetic patient, and mainly aims at solving the problem of unreasonable component allocation of an existing food for the diabetic patient. The food is prepared from squid viscera oligopeptide, composite vegetable oil and carbohydrate as main raw materials, and multivitamins and minerals as auxiliary materials. The unique effect of each component is given into a full play; and the components are assisted by one another to reach the synergistic effect and the efficacies of balancing nutrients, enhancing the immunity of the organism, improving the diabetes symptoms and improving the living quality of the patient. The food is available in raw material, safe, effective and free of a toxic or side effect.

The invention provides an application of diethyl n-butylmalonate in preparation of medicines for preventing and treating obesity, and belongs to the technical field of biomedicines. Diethyl n-butylmalonate can reduce body weight and liver weight in obese mice, prevent lipid accumulation in liver tissues, enhance fatty acid oxidation in obese mice and increase energy consumption so as to achieve weight losing effect. Moreover, Diethyl n-butylmalonate can improve glucose tolerance and insulin resistance, and has the effect of correcting obesity-related metabolic disorders.

The invention discloses a blood sugar lowering granule prepared from the following components in parts by weight: 5 to 20 parts of herba commelinae, 5 to 20 parts of herba portulacae, 5 to 8 parts ofsweet potato leaves, 3 to 7 of enteromorpha prolifera, 1 to 5 parts of radix puerariae, 1 to 5 parts of common yam rhizome and 5 to 20 parts of microcrystalline cellulose. The preparation method includes the steps of weighing the herba commelinae, herba portulacae, sweet potato leaves, enteromorpha prolifera, radix puerariae, and common yam rhizome according to weight parts, washing, chopping, andsoaking in water for 30 minutes or above; decocting in a traditional Chinese medicine decocting machine for 2 hours or above to extract a herb solution; adding water for decoction for 1 hour or aboveto extract a herb solution; combining the herb solutions of two times, then filtering to remove residues, concentrating at low temperature to a specific gravity of 1.2 to 1.5, then adding the auxiliary material microcrystalline cellulose, stirring evenly and placing in a spray-drying granulator to prepare granules; then sterilizing and performing sealing packaging.

The invention discloses blood-pressure-reducing and blood-fat-reducing tea. The blood-pressure-reducing and blood-fat-reducing tea is prepared from, by weight, 1-2 parts of fiveleaf gynostemma herbs,0.5-1 part of folium apocyni veneti, 2.9-4.2 parts of dark green tea, 0.5-1.5 parts of vine tea and 0.5-1.5 parts of glede tea. The five components of the composition all contain flavonoid substanceswith different contents and also contain other components respectively, wherein fiveleaf gynostemma herbs contain total saponins, folium apocyni veneti contains tannin, tea polyphenol, vitamin C, tannic acid and quercetin, the vine tea contains dihydromyricetin, the dark green tea contains tea polyphenol and lovastatin, and the glede tea contains gamma-aminobutyric acid GABA and selenium; the other ingredients and the flavonoid substances contained in the five components complement each other to achieve the better effect of reducing the blood pressure and the blood fat; the five components canmutually overcome side effects and improve the mutual pharmacological effects, the curative effect is definite, and no toxic and side effects are caused.

The invention provides a pharmaceutical composition for treating liver disease. Specifically, the pharmaceutical composition comprises a compound shown in the formula I and pharmaceutically acceptable excipients. The pharmaceutical composition is prepared into a solution by using water, wherein each 1ml of the solution contains 20mg of the compound shown in the formula I, the solution is measured according to the method in the appendix VI H of 2005 'China Pharmacopoeia'(II), and the pH value of the solution is 5.2-6.8. The invention also relates to a preparation method of the pharmaceutical composition. The pharmaceutical composition provided by the invention has pharmaceutical advantages.

The invention relates to a traditional Chinese medicine, and concretely relates to a traditional Chinese medicine for treating the diabetes. The raw materials of the traditional Chinese medicine comprise 1-4 parts by weight of wine cooked Rheum officinale, 3-8 parts by weight of Fructus Arctii, 5-18 parts by weight of Radix Astragali preparata, and 2-6 parts by weight of wine processed Rhizoma Coptidis, or 0.16-0.48 parts by weight of berberine, or 4-15 parts by weight of wine processed Amur Corktree Bark, or 5-20 parts by weight of wine processed Chinese mahonia leaf, or 4-20 parts by weight of wine processed Thalictrum aquilegifolium. A powder of the above raw materials is mixed with 5-10 parts by weight of a sesame paste to prepare pills or granules or tablets, and the pills or granules or tablets are externally coated with edible oil. The traditional Chinese medicine has the advantages of fast sugar reducing effect, large intensity, high efficiency, non-toxicity, and effective control of the diabetes.

The present invention discloses a purely natural medicine which is used for treating diabetes. The medicine comprises the ingredients of the following weight percent: 5 percent of ginseng, 5 percent of radix astragali, 5 percent of dwarf lilyturf root, 5 percent of fructus schizandrae, 5 percent of prepared rhizome of rehmannia, 5 percent of corns officinalis, 5 percent of tuckahoe, 5 percent of pollen, 5 percent of rhizoma anemarrhenae, 5 percent of spiral alga, 5 percent of Chinese goldthread, 8 percent of jellyfish, 8 percent of oyster, 8 percent of sea clam, 10 percent of black snake, andsimilarly black thorny ant. The medicine can restore the hematopoietic function by improving the hematopoietic microenvironment, and comprehensively strengthening the physical functions which comprise restoring the pancreatic function, secreting enough insulin, and correcting the turbulence of bran metabolism; thus the blood bran and blood can be normal; a plurality of diabetic complications can be eliminated correspondingly so that the patient can be rehabilitated. The medicine has the functions of benefiting marrow, generating blood, activating blood circulation, dissipating blood stasis, restoring normal blood, and so on, and is mainly used for treating the diabetes.

The invention discloses a traditional Chinese medicine preparation for treating high blood pressure. The traditional Chinese medicine preparation is characterized by being prepared from the followingtraditional Chinese medicine raw materials in parts by weight: 50-250 parts of cassia seeds, 50-300 parts of hawthorn and 200-600 parts of seaweed. The traditional Chinese medicine preparation is mainly used for reducing blood pressure, improving abnormalities of hemodynamics, hemorheology, vasoconstriction and the like of patients suffering from high blood pressure, adjusting fibrinolytic systemfunctions and platelet functions in blood and correcting metabolic disorders of various substances, has the effects of reducing blood pressure, reducing blood fat and resisting blood coagulation, andhas a remarkable prevention and treatment effect on high blood pressure. The traditional Chinese medicine preparation is simple in formula, low in cost, good in effect and capable of effectively preventing side effects caused by use of western medicines.

The invention relates to medicinal granules for reducing blood sugar, and belongs to the technical field of processing of health-care foods. The medicinal granules are prepared from the following components in parts by weight: 10-20 parts of resistant starch, 5-10 parts of resistant dextrin, 1-5 parts of radix puerariae, 1-3 parts of American ginseng, 5-10 parts of radix astragali, 5-10 parts of fiveleaf gynostemma herbs, 5-9 parts of lentinan and 2-5 parts of inulin. A preparation method of the medicinal granules comprises the following steps of uniformly mixing raw materials according to theformula, preparing fine particles, performing sterilizing and performing bagging. The medicinal granules prepared by the method are good in the effect of reducing blood sugar, can obviously reduce blood sugar concentration, are free from any side effects, and can nourish yin, tonify the kidney, balance yin-yang and correct metabolic disturbance of sugar, protein, fat and the like.

The invention discloses a composition for improving hyperglycemia and a preparation method thereof. The composition for improving hyperglycemia comprises the following effective components in parts byweight: 1-20 parts of Chinese yams, 1-20 parts of kudzuvine root; and 2-25 parts of walnuts; the preparation method comprises the following steps: a liquid medicine extraction step: adding water to soak the Chinese yam, kudzuvine root, cassia seed, semen cassiae and walnut, then heating and boiling, and filtering out a liquid medicine; a filtering step: heating and concentrating the liquid medicine, adding ethanol, refrigerating, filtering, and taking a filtrate; and a concentrating step: heating the filtrate, and evaporating out ethanol under reduced pressure to obtain a composition. The composition can be used as both medicine and food, and after a user eats the composition, metabolic disorder symptoms such as polyphagia, polydipsia, diuresis and weight loss of a diabetic patient can beimproved, good absorption and metabolism can be maintained, the physique of the user can be improved, and chronic complications of diabetes mellitus can be reduced.

The invention discloses sea buckthorn fruit extract moisturizing gel and a preparation method thereof. The sea buckthorn fruit extract moisturizing gel comprises the substances of sea buckthorn fruitpropyl gallate, tryptophan, amine oxidase, oleanolic sterol ester, sea buckthorn fruit sitosterol, oleanolic acid, glycerol, bletilla striata gum, normal propyl alcohol, a preservative, essence, deionized water and the like. Gallic acid has anti-inflammatory biological activity, esterification reaction and in-vivo SOD (superoxide dismutase) combined reaction are performed, and the effects of preventing aging, resisting oxidation and preventing allergy are achieved while water is replenished. The amine oxidase can remove free radicals generated during enzymatic reaction and non-enzymatic reaction in the body and remove toxic substances in the body. The oleanolic sterol ester improves the activity of oxidase in vivo, regulates lipid stability and corrects protein metabolic disorders. By adding the moisturizing anti-aging antioxidant substance and the reaction of the moisturizing anti-aging antioxidant substance in the body, the effects of preventing allergy, enhancing moisture retention,improving lipid metabolism and the like are achieved.

The invention discloses an emergency food and a preparation method thereof, and the preparation method comprises the following steps: mixing an aqueous solution of whey protein isolate and an oil solution of beta-carotene, and carrying out homogenization treatment to obtain a single-layer emulsion; adding Arabic gum into the single-layer emulsion, and carrying out homogenization treatment to obtain a layer-by-layer emulsion; and adding a mixed solution of trehalose and maltodextrin into the layer-by-layer emulsion, and performing freeze drying to obtain the emergency food. The prepared emergency food can meet normal nutritional requirements of a human body, the beta-carotene is wrapped by a layer-by-layer emulsion structure formed by the whey protein isolate and the Arabic gum, and the layer-by-layer emulsion structure is packaged by a glass packaging body formed by the trehalose and the maltodextrin, so that the stability of the emergency food is improved, and the shelf life of the emergency food is prolonged. Trehalose can participate in metabolism of the human body after entering the human body, human body metabolic disorder is corrected, low digestion and absorption efficiency of the emergency food caused by metabolic disorder is avoided, and the nutrient and energy supplementing effect of the emergency food is improved.

The invention relates to a medicament for treating kidney stone, which comprises the following components in parts by weight: 1 part of plantain, 1 part of Japanese climbing fern spore, 1 part of lalang grass rhizome, and 2 to 5 parts of fresh alive native crucian. The medicament is prepared from plantain, Japanese climbing fern spore, lalang grass rhizome and fresh alive native crucian, and has the effects of reducing fever and causing diuresis, cooling blood and removing toxicity. The drug effect can be quickly infiltrated into a human body and absorbed by decoction and oral administration, so that the medicament has the functions of clearing away heat and toxic materials, soothing liver and regulating qi, resolving stone and relieving pain, and can be used for effectively correcting imbalance of internal organ functions and metabolic disorders, so that body vital energy and blood, yin and yang can be recovered to balance, the kidney stones can be fundamentally treated from 'removing stones' and 'balancing qi and blood, yin and yang'. The medicament has the characteristics of being convenient to prepare, and having no side effect and no operation pain.

The Chinese medicine capsule preparation for curing diabetes is made up by using 10-odd Chinese medicinal materials of sea cucumber, astragalus root, Chinese yam and others. Said invented medicine can effectively raise sensitivity of is let cells, correct metabolic disorder, inhibit glycogenolysis, promote pancreatic cell secretion, raise immunological function, reduce blood fat, reduce blood sugar and can prevent and cure arteriosclerotic diseases. Its effective rate can be up to 95% and its cure rate can be up to 80%.