Micro-electrode array chip before retina in field of artificial vision

Abstract

The invention discloses a micro-electrode array chip before retina in the field of artificial vision. The micro-electrode array chip comprises a chip substrate, a lead buried in the chip substrate and micro-electrodes protruding the surface of the substrate and forming an array. The edge of the lower end of the chip substrate is provided with at least two lower suture line preformed holes; a micro-electrode arrangement lower area, a micro-electrode arrangement middle area, a micro-electrode arrangement upper area, a substrate reduction area and a substrate expansion area are sequentially arranged on the chip substrate from bottom to top; the substrate expansion area contains contacts corresponding to the electrode arrangement areas, and are connected with the micro-electrodes through the lead buried in the chip substrate; the chip substrate close to the lower end of the substrate reduction area is provided with at least three groups of two sclera cut suture line preformed holes, and two edges are respectively provided with at least two upper suture line preformed holes; and two sides of the substrate expansion area are provided with eye external suture line preformed holes. The micro-electrode array chip can stimulate retinal ganlion cells of the blind to recover partial vision of the blind, and avoids rhegmatogenous retinal detachment, choroidal hemorrhage and sympathetic ophthalmia caused by iatrogenic retinal breaks.

Description

technical field [0001] The invention relates to an ophthalmic medical device, in particular to a preretinal microelectrode array chip used in the field of artificial vision. Background technique [0002] The visual system is the most important source of information for human beings to understand and transform the objective world. The human visual system is composed of the refractive interstitium of the eye and the visual nervous system, forming a complete process of optical signal propagation, photoelectric conversion, and electrical signal processing and transmission, and finally perceived by the visual center combined with people's life experience. Although today's medical methods have effective treatments for many blinding eye diseases such as trachoma, cataract, glaucoma, etc., they are still not very effective for retinal diseases such as retinitis pigmentosa (RP) where the outer retina (photoreceptors) is destroyed. therapy. As far as RP is concerned, its incidence r...

AI Technical Summary

Problems solved by technology

[0005] 1. Fixing the microelectrode array on the anterior surface of the retina requires the use of titanium nails to punch holes in the retina, which increases the risk of rhegmatogenous retinal detachment;

[0006] 2. Titanium nails are placed on the posterior pole of the retina, where the blood supply of the choroid is rich, and it is easy to cause choroidal hemorrhage or even choroidal hemorrhage;

[0007] 3. Due to damage to the choroid (a part of the uvea), it is easy to induce uveitis, and even cause sympathetic ophthalmia in the fellow eye;

[0008] 4. Titanium nails are designed with barbs, which are not easy to take out after being nailed into the eyeball wall. If the microelectrode array needs to be taken out or replaced after a period of use, it will be very difficult;

[0009] 5. The microelectrode array can only stimulate the macular area of ​​the retina, but cannot stimulate other areas of the retina, that is, the patient can only restore part of the central vision, but the peripheral vision cannot be restored

[0010] 6. After the microelectrode array elicits the eyeball, the closure of the scleral incision is poor, and it is easy to form incision leakage

Images