High-ventilated degradable medicine-carrying skin wound dressing as well as preparation method and device thereof
A technology for skin wounds and air permeability, which is applied in the field of highly air-permeable and degradable drug-loaded skin wound dressings and its preparation, to achieve the effects of avoiding pain, inhibiting bacterial growth, and fast antibacterial performance
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[0023] Example Preparation of medicated skin wound dressing
[0024] Specific process flow such as figure 1 Shown: first mix a certain amount of chitosan (0.5~1.2g), water (15~30g) and lactic acid (0.2~1ml), and mix it at 40~60 O C. In a constant temperature water bath, use a magnetic stirrer to stir at high speed for 4 hours, the system is translucent golden yellow and viscous; then put the colloidal solution in a watch glass and put it in a low-temperature freezer O C) Freeze for 24 hours, then freeze-dry it to a fluffy sponge shape with a freeze dryer, which is solid chitosan lactate.
[0025] Dissolve the chitosan lactate in deionized water, prepare a 5-15% aqueous solution, add 1-5 grams of sodium hyaluronate solution, mix and stir; when the system is uniform and transparent, add tert-butanol Appropriate amount (concentration of tert-butanol is 3-15% of the entire system), continue to stir; when the system is uniform and transparent, add antibiotics (concentration of 5-15% of ...
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