Preparation method of root of Japanese banana extract and product and application thereof

An extract, the technology of plantain root, applied in the field of preparation of plantain root extract, can solve problems such as unclear

Inactive Publication Date: 2011-11-02
GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, it is not very clear which components or parts of fresh plantain root products are related to the treatment of diabetes. Therefore, it is necessary to conduct i...

Method used

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  • Preparation method of root of Japanese banana extract and product and application thereof
  • Preparation method of root of Japanese banana extract and product and application thereof
  • Preparation method of root of Japanese banana extract and product and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] Example 1: Fresh plantain roots are sliced ​​and crushed, squeezed with a juicer, extracted with n-butanol, concentrated under reduced pressure at 40°C to 65°C, dried under reduced pressure at 40°C to 65°C to obtain the extract Material X (corresponding to extract C).

Embodiment 2

[0071] Example 2: Fresh plantain roots are sliced ​​and crushed, soaked in 50% ethanol (30°C-60°C) and extracted 5 times, then the residue is squeezed, and the ethanol extract and squeezed juice are combined at 25°C-65°C Concentrate under reduced pressure until there is no alcohol smell, disperse with water, extract with n-butanol, concentrate under reduced pressure at 25°C-65°C, and dry under normal pressure at 25°C-65°C to obtain extract X (corresponding to extract F).

Embodiment 3

[0072] Example 3: The fresh plantain root is sliced ​​and crushed, first soaked in 75% ethanol (10°C-75°C) and extracted 6 times, then the residue is squeezed, and the ethanol extract and squeezed juice are combined, 35°C-75°C Concentrate under reduced pressure, dry under normal pressure at 35°C to 75°C, disperse with water, extract with n-butanol, concentrate under reduced pressure at 35°C to 75°C, and spray dry at 35°C to 75°C to obtain extract X (corresponding to extract F ).

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Abstract

The invention discloses a preparation method of root of Japanese banana extract and a product and application thereof. The preparation method comprises the steps of: slicing fresh root of Japanese banana, smashing, juicing by a juicer, extracting the juice by normal butanol, concentrating by pressure reduction, and drying to obtain an extract X; or dissolving the extract extracted by the normal butanol in water, loading on macroporous absorbent resin columns, respectively eluting with water and 30%-70% ethanol of which the volumes are 2-7 times of that of the columns, discarding the water eluent, collecting the ethanol eluent, concentrating by pressure reduction, and drying to obtain an extract Y. In the invention, the extract with hpyerglycemic effect (activity) is extracted from the root of Japanese banana, the extract has definite components, obvious pharmacological activity, stable nature, safety and reliability, and the extract can be used as a main component for processing a suitable pharmaceutical preparation for treating diabetes, and the pharmaceutical preparation has obvious curative effect proven by pharmacodynamics; and the raw material of the extract is easy to obtain, and the preparation process is easy to industrialize, thus promoting the full development and utilization of the medicinal resources in minority areas.

Description

technical field [0001] The invention relates to a preparation method of plantain root extract and its product and application, and belongs to the technical field of traditional Chinese medicine extracts. Background technique [0002] Diabetes mellitus is a metabolic disease characterized by hyperglycemia caused by defects in insulin secretion and / or its biological function. The disease is second only to tumors and cardiovascular and cerebrovascular diseases, and is listed as the third largest disease in the world. [0003] At present, about 360 million people in the world suffer from type II diabetes, accounting for 6% of the world's 6 billion population. About one person suffers from diabetes every 5 seconds, and one person dies from diabetes every 10 seconds. my country has become one of the countries with the fastest growing prevalence of diabetes in the world. The 2002 National Nutrition and Health Survey showed that there were more than 20 million diabetics in my coun...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P3/10A61K125/00
Inventor 王祥培钱海兵靳凤云吴红梅许士娜李雨生郝俊杰
Owner GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
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