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A compound preparation of traditional Chinese medicine and western medicine for preventing and treating bullfrog agalactiae streptococcosis and its preparation method

A technology of Streptococcus lactis and compound preparations, applied in antibacterial drugs, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problem of loss of therapeutic effect of pathogenic microorganisms, high infection rate and mortality of bullfrog Streptococcus agalactiae , loss of bullfrog farming and other issues

Inactive Publication Date: 2011-12-21
ZHEJIANG INST OF FRESH WATER FISHERIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The infection rate and mortality rate of bullfrog streptococcosis agalactiae are high, which has caused serious losses to the bullfrog breeding industry
The conventional treatment method for bullfrog agalactiae streptococcosis is chemical medicine plus antibiotics. Long-term use of antibiotics is likely to cause drug resistance of pathogenic microorganisms and lose the therapeutic effect, while Chinese herbal medicine has no residue and no drug resistance. Therefore, delete It is of great significance to prepare a compound preparation with rapid effect and long-lasting effect by combining the compatibility and curative effect of Chinese and Western medicines that have therapeutic effects on the disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Weigh 18% of Galla Chinensis, 8% of Andrographis paniculata, 17% of rhubarb, 15% of honeysuckle, 32% of starch, 10% of neomycin sulfate, fineness requirement: 100 mesh, weight loss on drying ≤10.0%; mix the Chinese medicine ingredients with starch until Completely mix; add neomycin sulfate and stir evenly to obtain a Chinese and Western medicine compound preparation for preventing and treating bullfrog agalactia streptococcus disease.

Embodiment 2

[0027] Weigh 22% of Galla Chinensis, 12% of Andrographis paniculata, 13% of rhubarb, 17% of honeysuckle, 28% of starch, 8% of neomycin sulfate, fineness requirement: 120 mesh, weight loss on drying ≤8.0%; mix the Chinese medicine ingredients and starch until Mix thoroughly; add neomycin sulfate and stir evenly to obtain a compound preparation.

Embodiment 3

[0029] Weigh 20% of gallnut, 5% of Andrographis paniculata, 15% of rhubarb, 10% of honeysuckle, 15% of neomycin sulfate, 35% of starch. The fineness requirement is: 80 mesh, weight loss on drying ≤10.0%; mix the starch with traditional Chinese medicine ingredients until complete Mix; add neomycin sulfate and stir evenly to obtain a compound preparation.

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PUM

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Abstract

The invention relates to a Chinese and western medicinal compound preparation for preventing and treating bullfrog streptococcus agalactiae diseases and a preparation method, and belongs to the technical field of fish medicines. The Chinese and western medicinal compound preparation is characterized by consisting of the following substances in percentage by weight: 15 to 25 percent of Chinese gall, 5 to 15 percent of common andrographis herb, 10 to 20 percent of rhubarb, 10 to 20 percent of honeysuckle flower, 5 to 15 percent of neomycin sulfate and 25 to 35 percent of starch. The Chinese andwestern medicinal compound preparation is prepared by combining the neomycin sulfate which has a treatment effect on germs and serves as a western medicine, the Chinese gall, the common andrographis herb, the rhubarb and the honeysuckle flower which serve as Chinese medicines and the starch serving as an auxiliary material, has obvious synergistic effect and high curative effect, lasting medicinal effect and low toxicity to the environment and can arouse quick response, and the tolerance is difficult to generate; and the preparation process is simple, easy to realize, safe and convenient to use, popularize and apply.

Description

Technical field [0001] The invention belongs to the technical field of fish medicine, in particular to a compound preparation of Chinese and western medicine for preventing and treating bullfrog agalactia streptococcus and a preparation method thereof. Background technique [0002] At present, streptococcus has become one of the main fish pathogens, and it harms many kinds of freshwater fish and sea fish such as salmon trout, red sea bream, flounder, ayu, coho salmon, and high mortality. Bullfrog agalactia streptococcus infection rate and mortality are high, causing serious losses to the bullfrog breeding industry. The conventional treatment of bullfrog agalactia streptococcus disease is chemical medicine plus antibiotics. Long-term use of antibiotics can easily cause pathogenic microorganisms to develop resistance and lose the therapeutic effect. Chinese herbal medicine has no residue and no drug resistance. Therefore, delete the selection Combining Chinese and Western medicine...

Claims

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Application Information

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IPC IPC(8): A61K36/708A61P31/04A61K35/64A61K31/7036
Inventor 周冬仁叶雪平罗毅志施伟达杭小英
Owner ZHEJIANG INST OF FRESH WATER FISHERIES
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