Chinese medicinal composition for treating gout, and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for the treatment of gout, can solve problems such as easy recurrence, failure to control the patient's condition in time, liver damage, etc., and achieve excellent anti-inflammatory and anti-gouty arthritis effects

Active Publication Date: 2013-04-17
ZHONGKE BOFANG XIAMEN BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine mainly adopts colchicine, non-steroidal anti-inflammatory drugs, glucocorticoids, probenecid and allopurinol in the treatment of this disease, but side effects are very prone to occur, such as gastrointestinal reactions, liver damage, Bone marrow suppression and other side effects, and easy to relapse, some patients are difficult to adhere to treatment or cannot be used due to side effects of important organs, so that the patient's condition cannot be controlled in time

Method used

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  • Chinese medicinal composition for treating gout, and application thereof
  • Chinese medicinal composition for treating gout, and application thereof
  • Chinese medicinal composition for treating gout, and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0092] Take 25g of horse chestnut, 20g of Tianqi, 30g of iron-clad gold, 15g of white back leaf root, 15g of reed root and 1g of borneol and mix them to obtain.

Embodiment 2

[0094] Take 25g of horse chestnut, 23g of Panax notoginseng, 32g of iron-clad gold, 18g of white back leaf root, 15g of reed root and 1g of borneol, crush them and mix, add 10 times the amount of distilled water to decoct 3 times, each 2h, combine the filtrate, concentrate, Concentration ratio (1.5:1), that is, 1ml extract is equivalent to 1.5g crude drug. Use 75% ethanol to remove impurities, precipitate for 24h, filter, concentrate under reduced pressure to a thick paste, and dry under reduced pressure to obtain, 1 gram of extract is equivalent 14.76g crude drug.

[0095] One gram of powder is equivalent to 12.99g of raw medicinal materials.

Embodiment 3

[0097] 20g of iron-coated gold is decocted with 10 times the amount of distilled water for 3 times, each time for 3 hours, the filtrate is combined, concentrated, and the concentration ratio (1.5:1) is 1ml extract equivalent to 1.5g crude drug (25℃), and 75% ethanol is used to remove impurities , Precipitate for 24h, filter, concentrate under reduced pressure to a thick paste, and dry under reduced pressure to obtain: 1 g extract is equivalent to 74.63 g crude drug

[0098] Decoction of 25g horse chestnut in 10 times distilled water for 3 times, 2 hours each time, combine the filtrate, concentrate, and the concentration ratio (1.25:1) is 1ml extract is equivalent to 1.25g crude drug (25℃), and use 50% ethanol to remove impurities. Precipitate for 24h, concentrate under reduced pressure to a thick paste, and dry under reduced pressure to obtain: 1 g extract is equivalent to 22.52 g crude drug

[0099] 18g reed root was decocted 3 times with 10 times the amount of distilled water, 1....

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Abstract

The invention relates to the field of natural medicines, in particular to a Chinese medicinal composition for treating gout and application thereof. The Chinese medicinal composition is characterized by being prepared from the following Chinese herbal medicines in part by weight: 20 to 30 parts of scandent schefflera stem and leaf, 15 to 25 parts of pseudo-ginseng, 20 to 40 parts of berchemia lineata, 10 to 20 parts of whitebackleaf mallotus root, 10 to 20 parts of reed rhizome and 0.5 to 1.5 parts of borneol. The medicinal effect test proves that the Chinese medicinal composition has the excellent antiinflammation and urarthritis resistance effects.

Description

Technical field [0001] The invention relates to the field of natural medicines, in particular to a traditional Chinese medicine composition for treating gout and its use. Background technique [0002] Gout (gout) is a disease caused by inherited or acquired causes of purine metabolism disorder and continuous increase in serum uric acid. The clinical features are hyperuricemia, recurrent gouty arthritis, tophi deposits formed by sodium urate salt, and tophi-induced chronic arthritis. If not properly treated, it usually develops into gouty nephropathy, which is often complicated by renal failure, arteriosclerosis, coronary heart disease, and cerebrovascular accidents. [0003] Gouty arthritis is the most common type of gout. The main victims are middle-aged and elderly men, accounting for 95%. Especially gouty arthritis is the initial clinical manifestation of about 95% of patients. Sudden onset and severe pain is the main reason for the first consultation of most patients. [0004]...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P19/06A61P19/02A61K31/045
Inventor 吴元通李运曼朱艺林吴正红
Owner ZHONGKE BOFANG XIAMEN BIO TECH
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