Improved method for synthesizing 2-mercaptobenzothiazole derivative

A technology of mercaptobenzothiazole and synthesis method, which is applied in the field of synthesis of 2-mercaptobenzothiazole derivatives, can solve the problems of insufficient conversion rate and high production cost, and achieve simple raw materials, high reaction yield, and economical synthesis The effect of time and cost
CN102304099AInactive Publication Date: 2012-01-04NANKAI UNIV
5 Cites 21 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANKAI UNIV
Publication Date
2012-01-04
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses an improved method for synthesizing a 2-mercaptobenzothiazole derivative. The method comprises the following steps of: putting relatively simple raw materials consisting of a phenylamine derivative, carbon disulfide and sulphur in a reaction kettle; introducing N2 till the reaction pressure is kept in a range of 6-15 MPa; raising the temperature to 200-260 DEG C; reacting for 2-5 h; dissolving the product by using alkali; filtering and removing side-effect impurities; and acidizing and separating the product, the content of which is above 99%. The reaction yield can be increased to 90-100% by optimizing a reaction condition. The method disclosed by the invention has the advantages that: the cost of reaction raw materials is saved; the reaction time is shortened; furthermore, the reaction purity and the yield are increased; and the method can be popularized for large-scale industrial production.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The technical scheme of the present invention relates to a synthesis method of 2-mercaptobenzothiazole derivatives. Background technique

[0002] 2-Mercaptobenzothiazole derivatives are widely used in industrial production, medicine, pesticide and other fields. Among them, 2-mercaptobenzothiazole (MBT) is used as a rubber vulcanization accelerator, a corrosion inhibitor for copper and copper alloy materials, and a reagent for determining silver, cadmium, iridium, lead, platinum, etc. Its derivatives can be used as thiazole-based vulcanization accelerators, fungicidal pesticides, ligands, dyes, vulcanization accelerators, proteinase inhibitors, and bactericidal, herbicidal and antiviral drugs. There are many kinds of mercaptobenzothiazole derivatives, and their functional effects and reported synthetic methods are also different; intermediate. The synthesis method reported in US4454148 is obtained by reacting 2-amino-4-methoxythiophenol with carbon d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More