Preparation method of dressing for treating burn combined with moist burn cream

Abstract

The invention provides a preparation method of dressing for treating burn combined with moist burn cream, which includes (1) dissolving hyaluronic acid and cellulose derivative in distilled water and regulating the pH value to be acidity; (2) adding cross linking agent in the solution in dropwise mode to conduct cross-linking reaction; (3) conducting ethanol precipitation, using ethanol to washing precipitate repeatedly and drying the precipitate in vacuum; and (4) swelling the dried precipitate in water solution containing zinc ions, freezing, drying and pressing the mixture to obtain the slice dressing. The dressing prepared in the method has grease scattering performance when treating the burn combined with the moist burn cream, cannot affect treating effect caused by the fact that the dressing absorbs ointment of the moist burn cream, simultaneously is capable of being attached to the surface of burnt skin to form a loose separation layer which is good in air permeability and capable of absorbing burn surface transduate, can effectively protect and close the burn surface to reduce scab area, and has functions of restraining scar tissue generation and accelerating burn surface union. The dressing enables dressing change to be easy to operate and cannot damage burn surface tissue due to flexibility and globality.

Description

technical field

[0001] The invention belongs to the field of biomedical materials, in particular to a preparation method of a dressing combined with moist burn ointment for treating burns. Background technique

[0002] Burns are one of the common diseases in surgery. According to statistics, burns are second only to traffic accidents in the number of deaths due to accidental injuries each year. The annual incidence of burns in my country is about 1.5% to 2%, that is, about 20 million people suffered burns of varying degrees, and about 5% of burn patients required hospitalization. For moderate and severe burns, a combination of systemic and local treatments is required. For wounds, in addition to preventing infection, it is necessary to promote their healing as soon as possible. At present, there are many ointments or dressings used for local treatment of burn wounds, among which traditional Chinese medicine ointment is a relatively effective treatment method. Our previous p...

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